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Vomiting clinical trials

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NCT ID: NCT06268717 Recruiting - Clinical trials for Irritable Bowel Syndrome

GI Alpha-Gal Study

Start date: October 17, 2023
Phase: N/A
Study type: Interventional

This is a double-blind, crossover food challenge study using pork with and without α-gal in patients with a clinical diagnosis of gastrointestinal (GI)- α-gal allergy, and to investigate the pathophysiology underlying their symptoms.

NCT ID: NCT06266819 Recruiting - Clinical trials for Hyperemesis Gravidarum

The Effect of Mint Flavored Chewing Gum on Hyperemesis Gravidarum Nausea Vomiting Severity, Coping With Stress and Anxiety Level in Pregnants With Hyperemesis Gravidarum

Start date: January 15, 2024
Phase: N/A
Study type: Interventional

In the research planned as a randomized controlled study, the experimental groups will be administered routine hyperemesis gravidarum (HG) treatment as well as chewing mint-flavored gum, while the control group will only receive routine HG treatment and no intervention will be performed. This study aims to contribute to the literature by investigating the effect of chewing mint-flavored gum on the severity of nausea and vomiting, coping with stress, and anxiety levels due to hyperemesis gravidarum in pregnant women.

NCT ID: NCT06254131 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Caesarean Section

Start date: February 10, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to estimate the effect of preoperative ondansetron lozenge on prevention of postoperative nausea and vomiting in caesarean section.

NCT ID: NCT06246240 Recruiting - Clinical trials for Pregnancy Nausea and Vomiting

Vitamin C Chewing Gum, Pregnancy Nausea and Vomiting

PregnancyNause
Start date: October 8, 2023
Phase: N/A
Study type: Interventional

Although there are studies in the literature examining the effects of chewing gum or using vitamin C on nausea and vomiting symptoms, no study has been found examining the effect of vitamin C gum on the severity of nausea and vomiting during pregnancy. This study aimed to investigate the effect of vitamin C gum on the severity of pregnancy nausea and vomiting.

NCT ID: NCT06241547 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

PONV Prevention Via Percutaneous Nerve Electrical Stimulation on PC6

Start date: January 12, 2024
Phase: Phase 2
Study type: Interventional

This study aims to certify the effectiveness of percutaneous electrical nerve stimulation at Pericardium 6 (PC6) via a wearable equipment during perioperative period on preventing postoperative nausea and vomiting.

NCT ID: NCT06208917 Recruiting - Clinical trials for Pediatric Solid Tumor, Unspecified, Protocol Specific

Ondansetron (ODF) Versus Ondansetron Intravenously for the Prevention of Chemotherapy-induced Nausea and Vomiting Compare in Children

Start date: July 9, 2023
Phase: Phase 3
Study type: Interventional

The purpose is to evaluate the efficacy of ondansetron oral soluble film plus dexamethasone in preventing chemotherapy-induced nausea and vomiting (CINV) with MEC/HEC chemotherapy in children with solid tumor.

NCT ID: NCT06200168 Recruiting - Nausea and Vomiting Clinical Trials

Electroacupuncture for the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients With Breast Cancer

Start date: December 20, 2023
Phase: Phase 3
Study type: Interventional

This randomized controlled phase III trial aims to evaluate the use of electroacupuncture in combination with olanzapine-containing standard quadruple antiemetic drugs for the treatment of nausea and vomiting induced by highly emetogenic chemotherapy (HEC) in patients with breast cancer. Furthermore, it will analyze the relationship between single nucleotide polymorphism and electroacupuncture treatment for chemotherapy-induced nausea and vomiting.

NCT ID: NCT06186141 Recruiting - Clinical trials for Patient-Controlled Analgesia

Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone

POPCORN
Start date: March 13, 2024
Phase: Phase 4
Study type: Interventional

POPCORN trial will compare the side effects and effectiveness of Morphine versus Oxycodone medication when prescribed for use as patient controlled analgesia (PCA) for pain relief for paediatric patients after-surgery. This trial is embedded into routine patient care using the hospital electronic medical record (EMR). Participants will be randomly assigned to either medication after they enrol in the study. The main questions the POPCORN trial aims to answer are: - 1. Is there a difference in the usage of medication to treat nausea and vomiting for those who received oxycodone PCA versus morphine PCA for post-surgery pain relief? - 2. Is there a difference in side effects or pain relief needed between the two groups? Study activities are as follows: - Participants enrolled to study during their pre-operative consultation - Participants are randomly assigned to morphine or oxycodone - No further study-specific activities expected from participant after enrolment and randomisation - Participant receives routine medical care as planned - Clinicians record assessments as per routine care in electronic medical record (EMR) - EMR data are extracted as trial data

NCT ID: NCT06170476 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in PONV

Start date: November 10, 2023
Phase: N/A
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled Dose-Finding study. About 200 subjects undergoing elective laparoscopic abdominal or gynecological surgery are planned to be enrolled and randomized into four groups by a ratio of 1:1:1:1.

NCT ID: NCT06151912 Recruiting - Clinical trials for Nausea, Postoperative

The Effect of Staple Line Reinforcement Procedures on Postoperative Nausea and Vomiting in Sleeve Gastrectomy

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Obesity is a significant public health problem. The only long-term effective treatment method is surgery. The most common surgical procedure is laparoscopic sleeve gastrectomy (LSG). However, after LSG, complications such as gastroesophageal reflux disease (GERD), insufficient weight loss, stenosis in the remnant stomach, and bleeding or leakage in the staple line (SL) may be encountered. The most severe complications are leakage and bleeding in sleeve gastrectomy, which can lead to many morbidities and mortality. Strengthening the staple line is an important option to prevent these complications. Methods such as fibrin adhesives, bioabsorbable patches and stitching of the stapler line are used to strengthen the stapler line. Nausea and vomiting, which occur in the postoperative period in 40% of patients who have undergone abdominal surgery and constitute a serious problem, are detected at an even higher rate in patients who have undergone bariatric surgery. Additionally, strengthening the staple line with various methods may increase the incidence of nausea and vomiting after LSG. Although there are studies in the literature investigating whether strengthening the staple line with buttress material or suture in laparoscopic sleeve gastrectomy affects the incidence of postoperative nausea and vomiting, there is no study investigating the effect of strengthening the staple line with fibrin glue on the incidence of postoperative nausea and vomiting. This prospective study aims to reveal whether there is a difference between strengthening the staple line with fibrin glue or suture in LSG regarding the incidence of postoperative nausea and vomiting and its effects on quality of life.