Vitiligo Clinical Trial
Official title:
Efficacy of 311-nm Ti:Sapphire Laser Versus 308-nm Excimer Laser Treatment in Vitiligo
A randomized controlled non-inferiority trial based on split-body was planned to compare the efficacy of 308-nm excimer laser and 311-nm Ti:Sapphire laser in patients with vitiligo.
The 308-nm excimer laser (EL) has been widely used for localized vitiligo. Recently, the
311-nm Ti:Sapphire laser (TSL) was developed to treat patients with vitiligo. To compare the
efficacy of TSL vs. EL in the treatment of vitiligo.
A randomized controlled non-inferiority trial based on split-body was planned. The paired
symmetric vitiliginous lesions will be randomized to either TSL or EL treatment groups. All
lesions will be treated twice weekly for a total of 12-week period. The degree of
repigmentation will be assessed as % from baseline by using a computer program every 4 weeks,
and the non-inferiority margin was set at 10%. Overall 16 patients will be enrolled.
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