Vitamin D Deficiency Clinical Trial
Official title:
Vitamin D Level in Patients With Pre-eclampsia, Eclampsia and Normal Full Term Pregnant
To compare 25(OH)D level in patients with pre-eclampsia, eclampsia and normotensive pregnant women as well as to study the prevalence of Vitamin D deficiency among the 3 groups.
200 patients with pre-eclampsia, 100 with eclampsia and 200 normotensive pregnant controls
attending Delivery/emergency department in Kasr Al Ainy hospital will be included in the
study (from March 2019 till September 2019). 25(OH) D level will be measured for the three
groups.
- Preeclampsia is defined as systolic BP >140 and/or diastolic BP>90 on two occasions, 4
hours apart in pregnant females>20 weeks, plus proteinuria >/= 1+ urine dipstick
protein.
- Eclampsia defined as tonic-clonic seizures in women with pre-eclampsia.
- Controls are normotensive pregnant females with no proteinuria and no other medical
disorders.
- The determination of 25(OH) D is based on a competitive enzyme-linked immunosorbant
assay (ELISA) using the 25(OH)D3/D2 ELISA system (ORGENTIC DIAGNOSTIKA GmbH, Germany)
Inclusion criteria:
Age 20-35 years Gestational age 30-40 weeks
Exclsion criteria:
Twin pregnancy Other medical conditions during prrgnancy Drugs that influence Vit D levels
eg.antiepileptics and antituberculous treatment.
;
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