Vitamin D Deficiency Still Growing

Vitamin D Deficiency Clinical Trial

Official title:

Is Vitamin D Deficiency Still Growing? Seven-Year Trend in KNHANES 2008-2014

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03304795
• Other study ID #: NRF-2015R1C1A1A01054333
• Status: Completed
• Phase: N/A
• First received: October 4, 2017
• Last updated: October 6, 2017
• Start date: January 1, 2008
• Est. completion date: December 31, 2014

Study information

• Verified date: October 2017
• Source: DongGuk University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Vitamin D deficiency has become one of the most prevalent health problems in modern society. However, there has been no study that has reported the trend of vitamin D status in Asia. This study investigated the trend of vitamin D status in Korea between 2008 and 2014.

This study is based on a representative national database acquired from the Korea National Health and Nutrition Examination Surveys (KNHANES) conducted from 2008 to 2014. Serum 25-hydroxyvitamin D [25(OH)D] levels were measured by radioimmunoassay among those aged 10 yrs or older. The temporal change of vitamin D status will be statistically analyzed.

Description:

Most epidemiologic studies that assessed vitamin D status in various populations have been performed in a cross-sectional design. Some studies from western countries have assessed the trends of vitamin D status over the past decades. However, there was no study that investigated the trend of vitamin D status in Asian population.

In the present study, an assessment of the seven-year trend of vitamin D status and the prevalence of vitamin D deficiency in the Korean population, based on the KNHANES conducted from 2008 to 2014 was performed.

The KNHANES is an ongoing surveillance system that has been conducted by the Division of Health and Nutrition Survey within the Korea Centers for Disease Control and Prevention to evaluate the health and nutritional status of the civilian non-institutionalized population of South Korea. Since the KNHANES was initiated in 1998, surveys for the KNHANES I (1998), KNHANES II (2001), KNHANES III (2005), KNHANES IV (2007-2009), KNHANES V (2010-2012), and KNHANES VI (2013-2015) have been executed, and the survey for KNHANES VII (2016-2018) is still in progress. The present study is based on the data acquired from the KNHANES IV-VI, conducted between 2008 and 2014. Among those participants, serum 25(OH)D levels were measured from 39,759 individuals (6,925 in 2008; 8,303 in 2009; 6,815 in 2010; 6,704 in 2011; 6,308 in 2012; 2,355 in 2013; and 2,349 in 2014) aged 10 years and older. Serum 25(OH)D concentration was categorized into 4 levels (<25, 25 to <50, 50 to <75, and ≥75 nmol/L) and the vitamin D deficiency was defined as the Serum 25 (OH) D concentration < 50 nmol/L.

Statistical analyses were conducted to evaluate the effects of participant characteristics (age, season, and residential region) on serum 25(OH)D concentrations, and the temporal change in the mean concentration of serum 25(OH)D over years 2008-2014.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 39759
• Est. completion date: December 31, 2014
• Est. primary completion date: December 31, 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 10 Years and older

Eligibility

Inclusion Criteria:

• Participants in the KNHANES from 2008 to 2014

• Participants who were examined for serum 25-hydroxyvitamin D level

Exclusion Criteria:

• Participants without serum 25-hydroxyvitamin D level data

Related Conditions & MeSH terms

• Vitamin D Deficiency

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
DongGuk University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Vitamin D deficiency	Serum 25-hydroxyvitamin D level less than 50 nmol/L	2008-2014