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Vestibular Migraine clinical trials

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NCT ID: NCT06417684 Not yet recruiting - Vestibular Migraine Clinical Trials

Comparison of Amitriptyline to Lifestyle Modification as Intervention for Vestibular Migraine

RCTVM
Start date: June 2024
Phase: Early Phase 1
Study type: Interventional

Vestibular migraine (VM) is one of the most common causes of vertigo attacks, affecting 1 - 5% of people. People with vestibular migraine have lower quality of life compared to others and some may experience completely debilitating symptoms. Symptoms include vertigo, nausea, head motion-induced dizziness, unsteadiness, balance problems, and lightheadedness. There is evidence the medication amitriptyline in isolation and also our lifestyle modification intervention in isolation can each help reduce symptoms of dizziness and headache in patients with VM. However, these data are observational and subject to various types of bias. The purpose of the current investigation is to determine outcomes from each intervention using randomized allocation of participants diagnosed with VM into either the amitriptyline arm or the lifestyle modification arm. We will measure for change in dizziness using the Dizziness Handicap Inventory (DHI) and for change in headache using the Headache Disability Inventory (HDI). For participants in the lifestyle modification arm, we will also measure for change in lifestyle factor to determine improvement on those intervention factors. Measures will be obtained pre-intervention to establish baseline, at 30 days, 60 days, and 90 days. We will also re-survey participants one year after initiation of intervention to determine adherence and status.

NCT ID: NCT05914207 Not yet recruiting - Vestibular Migraine Clinical Trials

Non-Pharmacological Treatment of Vestibular Migraine in Children and Adolescent

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Vestibular dysfunction has traditionally been linked to various conditions that affect older adults. Recent studies have shown that children and adolescents suffer from vestibular impairments, yet the numbers are still low due to some factors, including the non-typical presentations. Vestibular migraine has been found to be the most common condition of vestibular dysfunction among children and adolescents. Nonetheless, most children remain undiagnosed due to lack awareness and vague clinical presentations. Parallel to that, there has been no consensus regarding the management algorithm. Most children are managed with pharmacological management extrapolated from the adult algorithm. Many clinicians fail to understand that pharmacological treatments are not sustainable long-term and should focus on lifestyle modifications such as sleep and dietary habits and other non-pharmacological treatments such as deep breathing exercises and vestibular rehabilitation therapy. This study aims to investigate the effect of non-pharmacological treatment in managing children and adolescents with VM. The investigators will use a standardised questionnaire before and after interventions to investigate the effect of lifestyle modifications, simple vestibular rehabilitation exercises and deep breathing techniques in children and adolescents with VM. Lifestyle modifications and vestibular rehabilitation exercise is a more sustainable way of managing children and adolescents with VM, avoiding the side effects of medication, and is more cost-effective. If the non-pharmacological treatment shows promising results, the investigators will continue with multicentre randomised-controlled studies.

NCT ID: NCT05508139 Not yet recruiting - Vestibular Migraine Clinical Trials

The Role Of Vestibular Rehabilitation Therapy In Management Of Vestibular Migraine Patients

Start date: December 1, 2022
Phase:
Study type: Observational

1. To assess the criteria of positional vertigo in vestibular migraine patients 2. To assess the effect of vestibular rehabilitation therapy in management of positional vertigo in vestibular migraine patients

NCT ID: NCT04664088 Not yet recruiting - Vestibular Migraine Clinical Trials

Acupuncture for Prophylaxis of Vestibular Migraine

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

With its high incidence rate and low diagnosis rate, vestibular migraine (VM) can seriously affect patients' quality of life. Current treatment of VM mainly contain rescue treatment and prophylaxis, both of which are often pharmacological-based therapies and bring a series of unavoidable side effects, which leads to poor compliance of patients. Moreover, frequent VM attacks can seriously affect patients' daily life and work. Therefore, prophylaxis treatment is of great significance for VM patients. As a non-pharmarceutical therapy, acupuncture is widely used for a wide range of migrainous and emotional disorders. Thus, it might be an alternative treatment for VM, but current evidence remains inconclusive. The aim of this randomized controlled trial is to investigate the prophylactic efficacy and safety of acupuncture therapy in patients with VM.