Changing Vertical Self-motion Perception

Vestibular Function Tests Clinical Trial

Official title:

Changing Vertical Self-motion Perception After Trampoline Jumping; Assessing Otolith Function in an Elevator

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04200820
• Other study ID #: BASEC-Nr: 2019-01759
• Status: Completed
• Phase: N/A
• Start date: December 5, 2019
• Est. completion date: March 10, 2020

Study information

• Verified date: May 2020
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The objective of this study is to explore the "vertical self-motion perception" on in healthy young individuals using an elevator as accelerator. Secondary aim is to explore the effects of repeated vertical acceleration on vertical vestibular sensibility.

Description:

The detection of displacement is important information to maintaining balance, postural control, and gait during daily living activities. This detection of displacement or self-motion perception is accomplished by the human vestibular system, particularly the otolith organs, the sacculus and utriculus. Both primarily respond to whole-body acceleration or tilt in gravity. The saccule and utricle detect linear motion as well as the static orientation of the head relative to gravity, which is itself a linear acceleration. The saccule is more sensitive to vertical acceleration (sensing elevator acceleration) and the utricle is more sensitive to horizontal acceleration (sensing a car accelerate). The signals from the vestibular system are transmitted o the central nervous system for further processing.

Testing the otolith function is difficult since it always a combination of the tested inertial acceleration (t) and gravity (g). Therefore the Vector of acceleration is skew. An isolated vertical direction testing of the saccule is to our knowledge not done. Testing the function of the saccule in an elevator would eliminate the any horizontal accelerations other than gravity. Using the decelerations phase of an elevator ride during both up and down ride could give important inside of the self-motion perception (sensation of acceleration of a subject). The reaction force F which accts on the otolith would be maximal when the elevator ride downwards would stop. The force acting on the otolith when the elevator got upwards is breaking is smaller than g.

A better understanding the adaption of the self-motion perception could be beneficial for patients with hypersensitive vestibular functioning, e.g. patients with vestibular migraine. We hypothesized that (a) healthy subjects change the self-motion perception after hyper-stimulation with repeated vertical acceleration.

The objective of this study is to explore the "vertical self-motion perception" on in healthy young individuals using an elevator as accelerator. Secondary aim is to explore the effects of repeated vertical acceleration on vertical vestibular sensibility.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: March 10, 2020
• Est. primary completion date: March 1, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• Healthy young adults

• Signed informed consent after being informed

Exclusion Criteria:

• Acute pain

• Chronic neck pain

• Undergone Neck surgery

• Any vestibular disorder

• Fear of elevators / claustrophobia

• Dizziness handicap inventory score >30

Related Conditions & MeSH terms

• Vestibular Function Tests

Intervention

Diagnostic Test:
• Trampoline
During trampoline training that participants undergo constant change of vestibular stimulation. This triggers deep proprioception as well as other sensory inputs. This trigger might affect strength, body stability, muscle coordinative responses, joint movement amplitudes and spatial integration

Locations

Country	Name	City	State
Switzerland	University Hospital Zurich, Directorate of Research and Education, Physiotherapy & Occupational Therapy Research	Zurich	ZH

Sponsors (1)

Lead Sponsor	Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change of Vertical Self-Motion Perception Reaction Time (VSMPT)	The VSMPT reflects the time in which a person's ability to sense vertical acceleration. A Raspberry Pi 3 B+ with an inertial measurement unit (IMU) will measure the vertical acceleration of the elevator's acceleration. The subject will be asked to stop the stopwatch he/she feels acceleration / deceleration of the elevator ride. The reaction time and the duration of acceleration / deceleration will be measured. Data will be collected starting on the ground floor as the elevator travelled up to a stop at the higher floor (12 floors up). Thereafter the down ride will be measured.Five-elevator rides up and five down will be measured.	Changes from before and after the elevator rides will be assessed. The assessments will be executed one minute before and after the trampoline intervention. One assessment will take 15 minutes.
Secondary	Self-administered neck mobility assessment tool (S-ROM-Neck)	The S-ROM-Neck questionnaire is a self-administered questionnaire that uses visual analog scales (VAS) to measure pain-free active range of motion (ROM) for all neck movements. The patient is asked to place a mark on a 100 mm line (0 mm = "no movement possible" and 100 mm = "as far as possible"). The total score is the sum of the individual scores (min. score (600) = no restrictions and max. score (0) = total restriction)	5 minutes. At the start of the study and before the first elevator measurements the participants are asked to fill out the questionnaire.
Secondary	Dizziness handicap inventory (DHI)	The DHI is a validated, 25-item-self-report questionnaire to evaluate the self-perceived handicapping effects caused by dizziness. The DHI is categorized in three domains; functional (9 questions, 36 points), emotional (9 questions, 36 points) and physical (7 questions, 28 points). Patients will answer the questions with no (0 points), sometimes (2 points) and yes (4 points). The higher the score, the greater the handicap caused by dizziness.	5 minutes. At the start of the study and before the first elevator measurements the participants are asked to fill out the questionnaire.