Study of Image-Guided SBRT for Vertebral Metastases

Vertebral Metastases Clinical Trial

Official title: Phase II Study of Image-Guided Single Fraction SBRT With VMAT-FFF Technique for Vertebral Metastases

Status Terminated

Clinical Trial Summary

Based on the known efficacy of ablative single dose SBRT and VMAT technique in various solid tumors, investigators have designed this study to assess feasibility of SBRT in selected patients with spine metastases.

Clinical Trial Description

This is a prospective, phase 2 study. The main objectives are to assess acute and late side effects of single fraction SBRT for selected patients with vertebral metastases and to study the local control of disease in treated sites.

The schedule will be 1 fraction of 18 Gy delivered in one day with Volumetric Modulated Arc Therapy (VMAT) and Flattening filter-free (FFF) beams. ;

Related Conditions & MeSH terms

• Neoplasm Metastasis
• Vertebral Metastases

• NCT number: NCT02616887
• Study type: Observational
• Source: Istituto Clinico Humanitas
• Status: Terminated
• Start date: November 5, 2015
• Completion date: February 8, 2022