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Modification of the Local Abnormal Ventricular Activity Only — LAVAONLY  

Ventricular Tachycardia Clinical Trial

Official title:
Substrate Based Modification in Ventricular Tachycardia: Ablation of the Local Abnormal Ventricular Activity Only

Clinical Trial Summary

Local abnormal ventricular activity (LAVA) is composed of high-frequency, mainly low voltage signals that represent near-field signals from slow-conducting tissue and thus potential VT isthmuses. The identification of LAVA potentials and their modification have usually been a complimentary component of the substrate-based modification of scar related ventricular arrhtyhmias. With better identification through technical solutions and improved algorithms, LAVA modification may be feasible for treatment in therapy refractory VT.

Clinical Trial Description

As of 2019 we started LAVA modification only in a subset of patients with therapy refractory ventricular tachycardia. The cohort icludes 55% patient with ischemic cardiomyopathy and 45% with dilated cardiomyopathy. 80% are ICD recipients. These patients were now retrospectively analysed in depth. The endpoint is time to relapse of ventricular tachycardia or ICD shock or death due to malignant arrhythmia. We evaluated all patients we treated accordingly from March 2019 through October 2020. No patient was excluded. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05331716
Study type Observational
Source University of Kiel
Contact
Status Completed
Phase
Start date January 1, 2019
Completion date December 31, 2021
View Details
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