Graduated Compression Stockings (GCS) Pilot Substudy

Status Completed

Clinical Trial Summary

This is a pilot substudy to the PeriOperative ISchemic Evaluation-2 Trial (POISE-2), to assess the feasibility of adding graduated compression stockings (GCS) to POISE-2 as an intervention.

Clinical Trial Description

Objective: To determine if thigh-level graduated compression stockings (below-knee graduated compression stockings may be used if thigh level graduated compression stockings are not feasible, such as after knee surgery), started before surgery and worn until discharge and for a minimum of 10 days (whichever is longer), reduce symptomatic venous thromboembolism (proximal deep vein thrombosis or pulmonary embolism) in the 30 days after surgery. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01234064
Study type	Interventional
Source	McMaster University
Contact
Status	Completed
Phase	Phase 3
Start date	November 2010
Completion date	December 2011

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05347550` - Examining the Benefit of Graduated Compression Stockings in the Prevention of vEnous Thromboembolism in Low-risk Surgical Patients	N/A
Enrolling by invitation	`NCT05794165` - Antithrombin to Improve Thromboprophylaxis and Reduce the Incidence of Trauma-Related Venous Thromboembolism	Phase 2
Completed	`NCT02379806` - The SYMPTOMS - SYstematic Elderly Medical Patients Thromboprophylaxis: Efficacy on Symptomatic OutcoMeS - Study	Phase 3
Recruiting	`NCT03691753` - Safety and Efficacy Study of Fitaya Vena Cava Filter	N/A
Completed	`NCT02197416` - Safety of Dabigatran Etexilate in Blood Clot Prevention in Children	Phase 3
Recruiting	`NCT05378035` - DOAC in Chinese Patients With Atrial Fibrillation
Recruiting	`NCT05171075` - A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE	Phase 3
Completed	`NCT01895777` - Open Label Study Comparing Efficacy and Safety of Dabigatran Etexilate to Standard of Care in Paediatric Patients With Venous Thromboembolism (VTE)	Phase 3
Completed	`NCT05897697` - Assessing Women's Preferences for Postpartum Thromboprophylaxis: the Prefer-Postpartum Study
Completed	`NCT04735523` - Replication of the RECOVER-II Anticoagulant Trial in Healthcare Claims Data
Completed	`NCT04736420` - Replication of the EINSTEIN-DVT Anticoagulant Trial in Healthcare Claims Data
Completed	`NCT04736719` - Replication of the AMPLIFY Anticoagulant Trial in Healthcare Claims Data
Completed	`NCT02912234` - Effect of Clarithromycin on the Pharmacokinetics of Apixaban in Healthy Participants	Phase 1
Completed	`NCT02829957` - RAMBLE - Rivaroxaban vs. Apixaban for Heavy Menstrual Bleeding	Phase 2/Phase 3
Completed	`NCT02746185` - Cancer Associated Thrombosis, a Pilot Treatment Study Using Rivaroxaban	Phase 3
Completed	`NCT02334007` - Extended Low-Molecular Weight Heparin VTE Prophylaxis in Thoracic Surgery	Phase 1/Phase 2
Completed	`NCT02223260` - Tolerability , PK/PD and Safety of Dabigatran Etexilate Oral Liquid Formulation in Children < 1 Year of Age	Phase 2
Completed	`NCT02661568` - Description of Patients With Acute Venous Thromboembolism in the UK's Clinical Practice Research Datalink Linked With Hospital Episode Statistics Dataset (CPRD-HES)	N/A
Completed	`NCT01976988` - Prospective Study on Preoperative Versus Postoperative Venous Thromboprophylaxis in Patients Undergoing Major Colorectal Surgery	Phase 3
Completed	`NCT01431456` - Safety of DAbigatran and RIvaroxaban Versus NAdroparin in the Prevention of Venous Thromboembolism After Knee Arthroplasty Surgery	Phase 3