Vascular Function Clinical Trial
Official title:
Forearm Blood Flow Response to Acute Consumption of Black Tea
The study will explore the benefit of tea for microcirculation. Subjects will consume tea ar a placebo matched for taste and appearance in a blinded cross over design.
Epidemiological studies indicate that regular consumption of black tea reduces the risk of
cardiovascular diseases. Tea consumption can result in improvements in endothelial function
of conduit arteries as measured by flow mediated dilation.
Less is known however about its effects in other vascular beds. The study will test the
hypothesis that tea affects endothelial function in the muscle microcirculation. This will
be done by assessment of forearm blood flow using venous occlusion plethysmography after
consumption of black tea against or placebo in a randomised, full cross-over study in 20
healthy middle-aged to elderly subjects
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Basic Science
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