Outcome of Sub-inguinal Varicocelectomy on Normal Semen in Patients Complaining of Orchilagia With Normal Semen

Varices; Cord Clinical Trial

Official title:

the Effect of Sub-inguinal Varicocelectomy in Patients Complaining of Orchialgia With Normal Semen Analysis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03835143
• Other study ID #: varicocle pain
• Status: Completed
• Start date: March 12, 2019
• Est. completion date: January 12, 2020

Study information

• Verified date: April 2020
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

varicoclelectomy is done for subfertiltiy and varicocele induced orchialgia. The effect of varicocelectomy on semen analysis is controversial. Many articles report favorable outcomes and others do not.

Most study don't focus on varicocelectomy done for varicocele induced orchialgia,and those studies dont report on postoperative semen.

This study will focus on the effect of operation on the semen postoperatively .

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: January 12, 2020
• Est. primary completion date: September 12, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

1. Primary varicocele.

2. Patient's age more than 20 years.

3. Scrotal pain (after exclusion of other causes).

4. Normal semen analysis

Exclusion Criteria:

1. Secondary varicocele.

2. Recurrent varicocele.

Related Conditions & MeSH terms

• Varices; Cord

Intervention

Procedure:
• subinguinal varicocelectomy
varicocele ligation done at the level of subinguinal region

Locations

Country	Name	City	State
Egypt	Assuit Medical School	Assiut	Assuit

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

References & Publications (5)

Cayan S, Shavakhabov S, Kadioglu A. Treatment of palpable varicocele in infertile men: a meta-analysis to define the best technique. J Androl. 2009 Jan-Feb;30(1):33-40. doi: 10.2164/jandrol.108.005967. Epub 2008 Sep 4. Review. — View Citation

Cho CL, Esteves SC, Agarwal A. Novel insights into the pathophysiology of varicocele and its association with reactive oxygen species and sperm DNA fragmentation. Asian J Androl. 2016 Mar-Apr;18(2):186-93. doi: 10.4103/1008-682X.170441. Review. — View Citation

Kupis L, Dobronski PA, Radziszewski P. Varicocele as a source of male infertility - current treatment techniques. Cent European J Urol. 2015;68(3):365-70. doi: 10.5173/ceju.2015.642. Epub 2015 Oct 15. Review. — View Citation

Paick S, Choi WS. Varicocele and Testicular Pain: A Review. World J Mens Health. 2019 Jan;37(1):4-11. doi: 10.5534/wjmh.170010. Epub 2018 May 16. Review. — View Citation

Shabana W, Teleb M, Dawod T, Elsayed E, Desoky E, Shahin A, Eladl M, Sorour W. Predictors of improvement in semen parameters after varicocelectomy for male subfertility: A prospective study. Can Urol Assoc J. 2015 Sep-Oct;9(9-10):E579-82. doi: 10.5489/cua — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Pain improvement using Numeric Pain Rating Scale	semen analysis	3 months after the operation
Other	duppler	doppler will be done to evaluate the veins pre and postoperative	3 months after the operation
Primary	Grades of Motility of sperm in semen analysis	semen analysis	3 months after the operation
Secondary	Count of sperms in semen analysis	semen analysis	3 months after the operation