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Transauricular Vagus Nerve Stimulation Improves Postoperative Delirium in Elderly Patients — Vnstar  

Vagus Nerve Stimulation Clinical Trial

Official title:
Transauricular Vagus Nerve Stimulation（taVNS）Improves Postoperative Delirium in Elderly Patients: a Randomized Controlled Study

Clinical Trial Summary

According to the 3D-CAM scale, evaluate the incidence of Postoperative Delirium within 5 days after surgery in elderly patients receiving Transauricular vagal nerve stimulation.The results are expected to provide evidence of the safety and efficacy of perioperative prophylactic use of taVNS in the clinical application of improving postoperative brain health in elderly patients, as well as theoretical and practical basis for subsequent studies or clinical applications.

Clinical Trial Description

This study aims to conduct a prospective, randomized controlled clinical trial on the preventive use of Transauricular vagal nerve stimulation to improve the incidence of Postoperative Delirium in elderly patients undergoing anesthesia surgery. The intervention group will receive taVNS, while the control group will only wear a taVNS stimulator without current stimulation. The main outcome measure of the study was the incidence of POD within 5 days after surgery. Secondary outcome measures include incidence of new mild and severe postoperative neurocognitive impairment during hospitalization and 90 days, all-cause mortality rate at 90 days, incidence of related adverse events, and length of stay. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06421077
Study type Interventional
Source Beijing Tiantan Hospital
Contact Ruquan Han, MD
Phone 8610-59976660
Email ruquan.han@ccmu.edu.cn
Status Recruiting
Phase N/A
Start date May 21, 2024
Completion date December 31, 2025
View Details
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