Clinical Trials Logo
  1. Home
  2. Vaginosis, Bacterial
  3. NCT02139839

Exploratory Study to Evaluate the Effects of the Probiotics L. Rhamnosus GR-1 and L. Reuteri RC-14

Vaginosis, Bacterial Clinical Trial

Official title:
A Single-Center Exploratory Study to Evaluate the Effects of the Probiotics L. Rhamnosus GR-1 and L. Reuteri RC-14 on Subjects With Intermediate Nugent Scores

Clinical Trial Summary

The purpose of this study was to determine whether L. rhamnosus GR-1 and L. reuteri RC-14 delivered via capsules to the vagina of post-menopausal women over a three day course of treatment can restore and maintain a lactobacilli-dominated microbiota. Exploratory analysis of microbial ecology, human microarrays and multiplex immunological assessments are included to characterize potential effects.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02139839
Study type Interventional
Source Kimberly-Clark Corporation
Contact
Status Completed
Phase Phase 0
Start date September 2012
Completion date May 2013
View Details
See also
  Status Clinical Trial Phase
Enrolling by invitation NCT02558179 - Diagnosing Bacterial Vaginosis/Vaginitis (BV) Using the Gynecologene Test Method N/A
Completed NCT02314429 - Trial Evaluating the Safety of a Lactate Releasing Vaginal Ring for the Prophylaxis of Bacterial Vaginosis Phase 1
Completed NCT02272231 - Pathogenesis of Bacterial Vaginosis in Women Who Have Sex With Women
Recruiting NCT01448291 - Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers Phase 4
Recruiting NCT03500107 - Use of Blue Light Emitting Diode in the Treatment of Women With Bacterial Vaginosis: a Clinical Trial N/A
Completed NCT00153517 - Maternal Effects of Bacterial Vaginosis (BV) Treatment in Pregnancy Phase 2
Completed NCT04989543 - Study of the Composition and Bacterial Diversity of the Vaginal Microbiota in Healthy Versus Pathological Conditions (Bacterial Vaginosis) Using a Targeted Metagenomic Approach (RNA 16s) N/A
Completed NCT02641717 - Validity of Patient-Collected Wet Mounts N/A
Terminated NCT03943823 - Postmenopausal Pessary Users: Estrogen Versus Trimosan Phase 4
Completed NCT03134924 - Vaginal Practices in Human Immunodeficiency Virus (HIV) Positive Women in Zambia, a Bio-Behavioral Intervention "WASH-2" N/A
Completed NCT01293643 - A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077) Phase 3
Terminated NCT01153958 - Colposeptine for the Treatment of Bacterial Vaginosis Phase 4
Completed NCT00484653 - Identification and Impact of Vaginal Flora Anomalies Among Pregnant Woman N/A
Completed NCT05649735 - EFFICACY AND SAFETY OF OVA AND LAVAGE MEDICAL DEVICES IN THE TREATMENT OF NON-SPECIFIC VULVOVAGINITIS N/A
Completed NCT02860845 - Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections Phase 4
Not yet recruiting NCT00491270 - Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery Phase 3
Completed NCT01055106 - Dose Ranging Study of Metronidazole Vaginal Gel in the Treatment of Bacterial Vaginosis Phase 2
Terminated NCT01322971 - Efficacy Study of Preconception Treatment of an Asymptomatic Bacterial Infection in an Infertility Population N/A
Completed NCT04171947 - Vaginal Ovule With Flavonoid Tea Extract for the Correction of Imbalance in the Vaginal Environment N/A
Completed NCT02392026 - Safety and Tolerability of Metronidazole Gel 1.3% Phase 4