Understanding and Overcoming the Racial/Ethnic Inequalities in COVID-19 Vaccination Acceptance

Vaccine Refusal Clinical Trial

Official title:

Mind the Vaccination Gap: Understanding and Overcoming the Racial/Ethnic Inequalities in COVID-19 Vaccination Acceptance

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05238428
• Other study ID #: ETH2122-0265
• Status: Completed
• Phase: N/A
• Start date: February 3, 2022
• Est. completion date: March 5, 2022

Study information

• Verified date: May 2022
• Source: University of Essex
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

With the constant threat of new epidemic waves and the emergence of variants, COVID-19 resilience can only be attained when a sufficient level of immunity is achieved. Yet, in the US and the UK, COVID-19 vaccination campaigns have failed to secure consistent vaccination acceptance in racial/ethnic minority communities. Despite racial/ethnic minorities being more at risk from COVID-19, they are less vaccinated than the White majority. The investigators propose that current vaccination invitation messages are deemed less trustworthy by racial/ethnic minorities than the White majority and that this might partly explain reduced vaccination acceptance. To provide causal evidence of the role of trust and actionable insights, the investigators will experimentally assess the benefits of new invitation messages to receive the COVID-19 booster dose in large, racially/ethnically diverse samples in the US and the UK. Results will evidence how to increase message and source trustworthiness to foster trust and vaccination acceptance across racial/ethnic groups.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 4039
• Est. completion date: March 5, 2022
• Est. primary completion date: February 28, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

Exclusion Criteria:

• if participants complete the study in less than 5 minutes

• if participants complete the study without paying attention (as indicated by their answers to two attention check questions)

Related Conditions & MeSH terms

• COVID-19
• Vaccine Refusal

Intervention

Behavioral:
• Trust boost
The investigators adapt the wording of the vaccination invitation to foster trust and increase vaccination acceptance.

Locations

Country	Name	City	State
United Kingdom	Qualtrics. The data is gathered via an online platform.	London

Sponsors (4)

Lead Sponsor	Collaborator
University of Essex	Department of Health and Social Care, Kingston University, University of Southern California

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Trust perception	Perceived trustworthiness of the vaccine invitation. Participants will rate how trustworthy is the invitation message on a 5 point Likert scale (1: Untrustworthy 3: Not sure, 5: Trustworthy)	immediately after intervention
Primary	Vaccination appointment booking	Likelihood to book a vaccination appointment via the message. Participants will report if they would use the link in the message to book their vaccination appointment on a 5 point Likert scale (1: No, I would not, 3: Not sure/maybe later, 5: Yes, I would)	immediately after intervention