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Clinical Trial Summary

The study evaluates anti-inflammatory effects and safety of simvastatin in non-infectious uveitis.


Clinical Trial Description

3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors (statins) have been shown to reduce local and systemic inflammation in animal models of various autoimmune disorders including uveitis. In this open-label, randomized study clinical efficacy and tolerability of simvastatin 40 mg/day for 8 weeks is evaluated. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04183387
Study type Interventional
Source Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology
Contact
Status Completed
Phase Phase 2
Start date September 2014
Completion date January 2016

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