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Clinical Trial Summary

This project is designed to test the hypothesis that acyclovir is clinically useful for patients with refractory viral uveitis.


Clinical Trial Description

Approval of the study was obtained from the hospital's ethical committee. The study design and methodology followed the tenets of Declaration of Helsinki. All patients were provided with written informed consent and received a thorough explanation of the study design, aims, benefits and potential risks. This is a prospective non-comparative interventional study. Aqueous humor samples were collected from participants to virus detection. Participants will take oral acyclovir 100 mg three times a day and data will be collected prospectively with regard to ophthalmologic outcomes. Study participants will be followed for up to 12 months to determine efficacy, and an additional 30 days for safety reports. Descriptive statistics will be gathered on participant demographics, uveitis characteristics, change in immunosuppressive medications, number of responders, ophthalmologic measures and change in corticosteroid dose during the study period. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03389191
Study type Interventional
Source Tianjin Medical University
Contact Xiaomin Zhang, M.D.
Phone +86-13920023990
Status Recruiting
Phase N/A
Start date January 2017
Completion date December 2021

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