Uveal Melanoma Clinical Trial
Official title:
Assessing the Clinical Effectiveness of Serum Biomarkers in the Diagnosis of Metastatic Uveal Melanoma
Uveal melanoma is the most common primary intraocular tumor in adults. The local treatment
is effective, but patients still die of metastatic disease. It has been shown that early
diagnosis of a few isolated metastases can result in a clean surgical excision of the
metastases and an extension of the expected survival from 7-12 months to over 10 years on
some patients.
Many serum biomarkers are employed in Oncology. It makes sense to try the relevant ones in
the diagnosis of metastatic uveal melanoma.
The investigators hypothesis is that a soluble serum biomarker level changes upon
development of metastatic disease either by secretion by the tumor cells themselves or by
their environment. Detection of changes in biomarker level may lead to the diagnosis of
metastases before they can be detected by imaging modalities, thus allowing for early
treatment of the metastases and a better chance of success.
n/a
Observational Model: Cohort, Time Perspective: Prospective
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