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Uterine Leiomyoma clinical trials

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NCT ID: NCT04874246 Completed - Uterine Leiomyoma Clinical Trials

Comparison of Concentration of Vasopressin During Robot-assisted Laparoscopic Myomectomy

VALENTINE
Start date: May 10, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect of the concentration of vasopressin, which is used as a method for reducing blood loss in robot-assisted laparoscopic myomectomy.

NCT ID: NCT04819633 Completed - Uterine Leiomyoma Clinical Trials

Evaluating Serum Sestrin in Leiomyoma Patients

Start date: January 1, 2021
Phase:
Study type: Observational

Leiomyomas are the most common benign neoplasms of women's reproductive system affecting 20-30% of women within the reproductive ages. Sestrins are serum proteins which are highly expressed under circumstances of DNA damage, hypoxia and oxditive stress and play an important role in autophagia. The aim of this study is to evaluate the relationship of serum sestrin proteins with development of leiomyomas.

NCT ID: NCT03847077 Completed - Uterine Leiomyoma Clinical Trials

Trial of a Patient Education Tool For Leiomyoma

PETAL
Start date: October 21, 2015
Phase: N/A
Study type: Interventional

The goal of this study was to assess whether using a multimedia tool would enhance patient education and counseling on uterine leiomyomata.

NCT ID: NCT03751124 Completed - Uterine Fibroids Clinical Trials

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Start date: October 16, 2018
Phase: Phase 3
Study type: Interventional

The objectives of this randomized withdrawal study are to evaluate the long-term efficacy and safety of the combination of relugolix, estradiol (E2) and norethindrone acetate (NETA), once daily, for up to 104 weeks in patients with uterine fibroids who have completed a total of 52 weeks of treatment, including a 24-week treatment period in a parent study (study MVT-601-3001 or MVT-601-3002) and a 28-week treatment period in the open-label extension study (MVT-601-3003), and who meet the definition of responder, defined as a patient who demonstrates a menstrual blood loss of < 80 mL and at least a 50% reduction from parent study baseline menstrual blood loss volume on the alkaline hematin analysis of the feminine products returned at Week 48 in the extension study.

NCT ID: NCT03535610 Completed - Uterine Leiomyoma Clinical Trials

Uterine Artery Embolization With Microspheres in Patients With Leiomyoma.

EMBOSOFT I
Start date: August 13, 2018
Phase: N/A
Study type: Interventional

To evaluate the therapeutic response to uterine artery embolization in 30 patients with leiomyoma using the microspheres Embosoft (Embosoft® - Scitech Medical).

NCT ID: NCT03328260 Completed - Uterine Leiomyoma Clinical Trials

High Intensity Focused Ultrasound in Uterine Myoma

Start date: December 12, 2017
Phase: N/A
Study type: Interventional

Aim to evaluate the efficacy of safety of newly developed, high intensity focused ultrasound device in women with symptomatic uterine leiomyoma

NCT ID: NCT02059954 Completed - Uterine Fibroids Clinical Trials

Vaginal vs. Laparoscopic Hysterectomy

Start date: January 2014
Phase: N/A
Study type: Interventional

Hysterectomy for benign indication is one of the most common surgical procedures in women. Numerous reviews and guidelines recommend the vaginal approach for benign hysterectomy, but the proportion of laparoscopic (and robotic) hysterectomies is increasing. This study will compare a range of clinical and subjective outcomes of vaginal vs. total laparoscopic hysterectomy. Outcomes include operating time, postoperative recovery, return to work as well as cosmesis, quality of life and sexual health.

NCT ID: NCT02049242 Completed - Uterine Leiomyoma Clinical Trials

Uterine Tourniquet at Open Myomectomy

Start date: January 2014
Phase: N/A
Study type: Interventional

The aim of study is to compare triple tourniquet vs. single tourniquet to reduce blood loss at open myomectomy.

NCT ID: NCT01715597 Completed - Uterine Leiomyoma Clinical Trials

Study on the Effect of Intravenous Ascorbic Acid on Intraoperative Blood Loss in Women With Uterine Myoma

Start date: December 2012
Phase: Phase 3
Study type: Interventional

The investigators want to know whether the intravenous ascorbic acid would reduce the blood loss during laparoscopic myoma surgery. The investigators randomized patients into intravenous ascorbic acid group and placebo group and examined the blood loss in both groups.

NCT ID: NCT01468402 Completed - Uterine Leiomyoma Clinical Trials

Predictive Factors of Pelvic Magnetic Resonance in the Response of Arterial Embolization of Uterine Leiomyoma

Start date: September 2008
Phase: N/A
Study type: Observational

The purpose of this study is to determine predictive factors in the pelvic magnetic resonance in the response of arterial embolization of uterine leiomyoma.