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Uterine Cervical Neoplasms clinical trials

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NCT ID: NCT04154358 Not yet recruiting - Cervical Cancer Clinical Trials

Implementing HPV DNA Self-Collection to Increase Rates of Cervical Cancer Screening in Transgender Men

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

Transgender men are individuals born genetically female that have a gender identity that is incongruent with their biological sex. For those who have begun or completed transition, they may present as males but still have a uterus and cervix. Thus far, no distinction has been made between routine cervical cancer screening guidelines in non-transgender women and those for transgender men, despite wide variations in sexual practices, including lifelong vaginal abstinence. The purpose of this study is to offer transgender men seen at clinic visits self-collected HPV testing to evaluate for improved cervical cancer screening rates, as well as a survey to further investigate sexual practices, rates of appropriate screening prior to being offered self-collection, and barriers to obtaining appropriate care.

NCT ID: NCT04154319 Completed - Cervical Cancer Clinical Trials

HPV Vaccination Among Daughters of Latina Immigrants

Start date: June 15, 2012
Phase: N/A
Study type: Interventional

The overall goal of this study to promote HPV vaccine uptake among daughters of Latina immigrants between the ages of 9 and 12.

NCT ID: NCT04150575 Active, not recruiting - Cervical Cancer Clinical Trials

A Clinical Study to Evaluate Efficacy and Safety of HLX10 Combined With Albumin-Bound Paclitaxel in Patients With Advanced Cervical Cancer Who Have Progressive Disease or Intolerable Toxicity After First-Line Standard Chemotherapy

Start date: March 10, 2020
Phase: Phase 2
Study type: Interventional

This is a single-arm, open-label, multicentre, phase II clinical study.Subjects can only enter this study after they meet the inclusion and exclusion criteria.All enrolled patients will receive the treatment with HLX10 combined with albumin-bound paclitaxel, every 3 weeks, until progressive disease, initiation of new anti-tumour therapy, death, intolerable toxicity. Albumin-bound paclitaxel may be used for up to 6 cycles and HLX10 for up to 2 years.

NCT ID: NCT04138992 Recruiting - Clinical trials for Disease Free Survival

A Study on the Efficacy and Safety of Bevacizumab in Untreated Patients With Locally Advanced Cervical Cancer

Start date: August 1, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

To verify the clinical efficacy and safety of bevacizumab in treating local advanced cervical cancer, present study was designed to investigate the clinical results of bevacizumab combined with concurrent chemoradiotherapy (CCRT) in local advanced cervical cancer

NCT ID: NCT04133610 Completed - Cervical Cancer Clinical Trials

HPVPro Study: Comparison of HPV Detection in Clinician-collected Cervical Swabs and Self-sampled Cervicovaginal Swabs

HPVPro
Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Comparison of the detection of human papillomavirus DNA in paired physician-obtained cervical swabs and self-sampled cervicovaginal swabs and evaluation of HPV prevalence in Czech women screening population.

NCT ID: NCT04121975 Recruiting - Cervical Cancer Clinical Trials

CCRT Combined With Endostar for the Treatment of Locally Advanced Cervical Cancer

Start date: August 1, 2019
Phase: Phase 2
Study type: Interventional

This was a prospective, single arm, phase 2 trial. Adult Patients with histologically confirmed locally advanced cervical cancer were enrolled to receive the treatment of concurrent chemoradiotherapy combined with Endostar. The primary endpoint was progression-free survival (PFS) rate at 1 year. The secondary endpoints were PFS, overall survival (OS) and safety.

NCT ID: NCT04114968 Recruiting - Mass Screening Clinical Trials

Offering Cervical Cancer Screening to Older Women

Start date: September 30, 2019
Phase:
Study type: Observational

This study evaluates the effect and feasibility of expanding the target population in the Danish cervical cancer screening program to include women aged 65 to 69 years. The study also evaluates if HPV self-sampling constitutes an appropriate screening method among older women.

NCT ID: NCT04113902 Completed - Health Education Clinical Trials

The Effects of Health Education About Human Papilloma Virus and Cervical Cancer Prevention on Knowledge, Attitudes, Beliefs and Behaviors

Start date: December 18, 2018
Phase: N/A
Study type: Interventional

Aim: To determine the effects of health education about Human Papilloma Virus infection and cervical cancer prevention on knowledge, attitudes, beliefs and behaviors of adolescent girls and their mothers. Background: To combat with cervical cancer, it is urgent that prevention Human Papilloma Virus related disease all around the world. Design: A randomized trial with a control group (n=108) and an intervention group (n=108). Methods: The study was applied between January to June 2019 in the two different adolescent outpatient clinics in Turkey. The outpatient clinics were randomly assigned as intervention and control groups by numbering and opaque and sealed envelopes. Based on the intention-to-treat principle, all participants were analyzed according to the group they were assigned to, regardless of whether they received the intervention or not. In addition to the routine clinical practice, the adolescent girls and their mothers who participated in the intervention group were given health education twice in the first interview and in the fifth week. Follow-up continued for 12 weeks. The adolescent girls and their mothers in the control group received routine clinical practice. The effects of health education were evaluated with Human Papilloma Virus Knowledge Scale and Health Belief Model Scale for Human Papilloma Virus and its Vaccination. Impact: Human Papilloma Virus vaccine, which has an important place in primary protection from cervical cancer, is expected to provide effective results by facilitating access to vaccine accompanied with health education.

NCT ID: NCT04113096 Recruiting - Clinical trials for Stage IV Breast Cancer

Dibenzyl Trisulphide (GUINEAHEN WEED) for Stage IV Cancer

Start date: October 1, 2018
Phase: Early Phase 1
Study type: Interventional

This study is being done to find the effect of Dibenzyl Trisulphide (active ingredient in Guinea Hen Weed in combination in patients with stage four cancer of the breast, prostate, cervix and colon.

NCT ID: NCT04111835 Completed - Cervical Cancer Clinical Trials

HPV Testing In Polish POpulation-based Cervical Cancer Screening Program.

HIPPOPROJECT
Start date: October 28, 2019
Phase: N/A
Study type: Interventional

The HIPPO PROJECT is a randomized healthcare study nested in the OCCSP in Poland. This project will assess the performance of the new screening test (HR HPV test) before its implementation in Poland.