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NCT01091402 Clinical Trial

Autologous Serum Skin Test and Serum IL-18 Levels in Chronic Idiopathic Urticaria and Respiratory Allergic Diseases

Urticaria Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01091402
Other study ID # 1
Secondary ID
Status Completed
Phase N/A
First received March 23, 2010
Last updated March 23, 2010
Start date January 2009

Study information
Verified date January 2009
Source Eskisehir Osmangazi University
Contact n/a
Is FDA regulated No
Health authority Turkey: Ethics Committee
Study type Observational

Clinical Trial Summary

One of the proposed mechanisms in CU is autoimmunity. It was shown by a positive response to autologous serum skin test (ASST)in almost half of chronic urticaria (CU) patients. IL-18 also play a role in autoimmune disorders. The investigators aim was to investigate the relationship of ASST and IL-18 in CU and respiratory allergic diseases.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 16 Years and older
Eligibility Inclusion Criteria:

- adult patients

- chronic urticaria patients

- stable asthma patients

- allergic rhinitis patients with sensitized to pollens

- normal controls without atopic and skin disease.

Exclusion Criteria:

- unwillingness to the study

- other dermatological problems that could affect the skin test

- use of antihistamine drugs

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Intervention

Procedure:
• autologous serum skin test, serum IL-18

Locations
Country Name City State
Turkey Eskisehir Osmangazi University Eskisehir

Sponsors (1)
Lead Sponsor Collaborator
Eskisehir Osmangazi University

Country where clinical trial is conducted

Turkey, 

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