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Urolithiasis clinical trials

View clinical trials related to Urolithiasis.

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NCT ID: NCT05027971 Completed - Clinical trials for Benign Prostatic Hyperplasia

Flexiva Pulse Registry

Start date: November 1, 2021
Phase:
Study type: Observational [Patient Registry]

To obtain post-market safety and efficacy data for FlexivaTM Pulse High Power Single-Use Laser Fibers during lithotripsy and soft tissue procedure of holmium laser enucleation of the prostate (HoLEP).

NCT ID: NCT04697706 Completed - Urinary Stone Clinical Trials

Effect of a High Citrate Beverage on Urine Chemistry in Urinary Stone Disease

Start date: September 1, 2020
Phase: Early Phase 1
Study type: Interventional

This study will investigate the effect of a patented high citrate beverage on urine chemistry in patients with urinary stone disease (USD). It is a minimal risk study of an over-the-counter beverage called Moonstone, which is commercially available. This study is considered preparatory for the RO-1 and is not intended to produce a definitive outcome regarding kidney stones.

NCT ID: NCT04695951 Completed - Urolithiasis Clinical Trials

Efficacy and Safety of Renalof® in the Removal of Calculi Smaller Than 10 mm Located in the Reno-Ureteral Tract

Start date: August 1, 2019
Phase: Phase 2
Study type: Interventional

Given the high recurrence of urolithiasis in patients, the search for less aggressive and preventive treatments is increasingly necessary. Renalof® is presented as an alternative to herbal medicine being a product that, due to its diuretic and demineralization properties of kidney stones, has been widely used in this patient population, disintegrating and eliminating calcium oxalate and struvite stones in a painless in the genitourinary system. With the objective of determining the efficacy of this therapy, an observational, prospective, randomized, single-blind, two-arm study was carried out: treatment group with Renalof® and control group, placebo.

NCT ID: NCT04668586 Completed - Urolithiasis Clinical Trials

Laser Lithotripsy During URS - Holmium vs Thulium

Start date: January 14, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to compare URS lithotripsy performed with Holmium:YAG laser and Thulium Fiber Laser. The study is designed as a prospective clinical randomised trial, where the study participants are randomised to either URS with Holmium:YAG laser or URS with Thulium Fiber Laser. The outcomes of the URS procedures are compared for the two treatment arms.

NCT ID: NCT04594161 Completed - Kidney Diseases Clinical Trials

Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis

STONE
Start date: July 15, 2020
Phase: N/A
Study type: Interventional

To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or kidney function deterioration) caused by urolithiasis.

NCT ID: NCT04582019 Completed - Urolithiasis Clinical Trials

Safety and Effectiveness of Ureteral DJ Stent With Magnet (Blackstar, Urotech) Removal Under Ultrasound Control

Start date: August 14, 2020
Phase: N/A
Study type: Interventional

Evaluation of safety and effectiveness of ureteral DJ stent with magnet (Blackstar, Urotech), severity of stent-association symptoms and pain level syndrome after stent extraction compared with stent extraction by flexible cystoscope

NCT ID: NCT04571359 Completed - Urolithiasis Clinical Trials

Spot Urine Oxalate to Creatinine Ratio and 24 Hours Urinary Oxalate

Start date: February 1, 2019
Phase:
Study type: Observational [Patient Registry]

The evaluation of 24 hour urinary oxalate excretion is the gold standard for diagnosing Hyperoxaluria in patients with recurrent urolithiasis. The relationship of oxalate measurement between spot and 24 hour urine sample has not been studied in Pakistani population before. Thus, it is necessary to see if spot urine samples show good correlation with 24 hour urine samples in our population where the frequency of hyperoxaluria in patients with urolithiasis is reported to be 64.5%. Also, the various pre analytical issues associated with 24 hour urinary collection which may lead to the incorrect or misdiagnosis, need for duplicate testing consuming extra resources and man power. We therefore, in this study, want to see the correlation between 24 hour urinary oxalate and oxalate to creatinine ratio. The aim of our study is to determine the relationship between 24 hour urinary oxalate and spot urine oxalate to creatinine ratio and to identify if oxalate to creatinine ratio can be used as an alternative to 24 hour urinary oxalate

NCT ID: NCT04387617 Completed - Urinary Stone Clinical Trials

A Study to Assess the Effect of Cannabidiol Oil on Pain After Ureteroscopy for Kidney Stones

Start date: February 15, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine if CBD oil has any effect on decreasing postoperative pain control following ureteroscopy for urinary stone disease, and to determine if CBD oil has any effect in decreasing the amount of postoperative opioids (commonly used drug) used by patients after undergoing ureteroscopy for urinary stone disease.

NCT ID: NCT04380675 Completed - Urolithiasis Clinical Trials

Music During ESWL for Entire Treatment

Start date: November 2, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate if music listening relieves pain and discomfort during Extracorporeal Shock-Waves Lithotripsy (ESWL).

NCT ID: NCT04354181 Completed - Urolithiasis Clinical Trials

Urine Biomarker for Stone Recurrence

Start date: July 24, 2020
Phase:
Study type: Observational

Despite the advent of treating stones with Extracorporeal Shock Wave Lithotripsy (ESWL) and Percutaneous nephrolithotomy (PCNL), the recurrence rate for renal stones remains high and this may be due to poor compliance of patients with dietary and fluid advice, age, metabolic abnormalities, medicines and the formation of "new stones" from clinically insignificant residual fragments (CIRF). Though some patients become stone-free after ESWL/PCNL or open surgeries, the majority develop "new stones" and it is difficult to predict when these stones will recur until either they have imaging perform or they developed symptoms. However, the use of regular imaging for monitoring will be costly and involve radiation exposure. Therefore, a diagnostic tool is needed to enable the clinician and/or patient to monitor for stone recurrence. In the previous studies, some urine markers were identified that are related to stone formation. The relationship of these urine markers with the recurrence of renal stone will be further explore in this study. Also, potential markers that could predict stone recurrence will be identified, and hence earlier intervention could be offered to patients.