Modified Reporting of Positive Urine Cultures Collected From Long Term Care

Urinary Tract Infections Clinical Trial

Official title:

Modified Reporting of Positive Urine Cultures Collected From Long Term Care, a Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03554603
• Other study ID #: MUN-04
• Status: Completed
• Phase: N/A
• Start date: November 5, 2018
• Est. completion date: July 31, 2019

Study information

• Verified date: July 2023
• Source: Memorial University of Newfoundland
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Asymptomatic bacteriuria (AB) is a condition in which bacteria are detected in urine culture without urinary symptoms. The inappropriate use of antibiotic treatment for AB selects bacterial flora to express resistance mutations. Reducing inappropriate antibiotic use for AB is difficult, since the microbiology laboratory cannot distinguish patients with AB. The investigators study will use a restricted laboratory report requesting the physician to call the laboratory for culture results. The restricted report may reduce the rate of inappropriate treatment of AB.

Description:

Positive urine cultures during the study period will be randomized to restricted microbiology laboratory reporting or standard microbiology laboratory reporting. Physician or patient consent will not be collected. Patient records will be assessed by the investigator to determine if patients have AB or urinary tract infection. Physician antibiotic treatment decision in both groups will be collected.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 100
• Est. completion date: July 31, 2019
• Est. primary completion date: July 31, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

1. Consecutive positive urine cultures collected from patients admitted to Long term care facilities will be included. All methods of urine collection will be included (midstream, in-and-out catheterization, indwelling catheter).

Exclusion Criteria:

1. Positive urine cultures not collected from Long term care facility patients

2. Pregnancy

3. Antibiotic treatment at the time of collection

4. Patients known to have blood neutrophils <1.0 within 7 days of urine collection

Related Conditions & MeSH terms

• Asymptomatic Bacteriuria
• Bacteriuria
• Urinary Tract Infections

Intervention

Behavioral:
• Modified Report
An abbreviated version of the microbiology report indicating that growth is present and the physician should call the lab for further details if clinically important.

Locations

Country	Name	City	State
Canada	Health Sciences Center	Saint John's	Newfoundland and Labrador

Sponsors (1)

Lead Sponsor	Collaborator
Memorial University of Newfoundland

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Proportion of Asymptomatic Bacteriuria Treated With Antibiotics and Urinary Tract Infection Treated With Antibiotics	Number of Participants Who Received Appropriate Antibiotic Treatment	7 days