Urinary Tract Infection Clinical Trial
Official title:
Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial
Urinary-tract infection (UTI) is the most common type of hospital-acquired infection (30% of all). The purpose of this study is to determine whether antibiotic prophylaxis for urinary catheter removal is useful at preventing catheter-associated urinary-tract infection.
Status | Completed |
Enrollment | 100 |
Est. completion date | April 2007 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Urethral catheter in situ for at least 3 days (72h) Exclusion Criteria: - Pregnancy - Impaired renal or hepatic function (serum creatinine > 150 mmol/l, serum transaminases > 75 IU/l) - Fever - Symptomatic urinary tract infection - Antibiotic use = 48 hours before urinary catheter removal - Allergy to trimethoprim-sulfamethoxazole or ciprofloxacin - Urologic pathology |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
Netherlands | Sint Antonius Hospital | Nieuwegein | Utrecht |
Lead Sponsor | Collaborator |
---|---|
St. Antonius Hospital |
Netherlands,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Symptomatic bacteriuria | |||
Primary | Asymptomatic bacteriuria | |||
Secondary | Antibiotic resistance patterns |
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