Peppermint Oil for Urinary Retention

Urinary Retention Clinical Trial

Official title:

Evaluating the Use of Peppermint Oil for Postpartum Women With Urinary Retention

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT05259800
• Other study ID #: 21-065
• Status: Enrolling by invitation
• Phase: N/A
• Start date: October 5, 2021
• Est. completion date: March 30, 2026

Study information

• Verified date: February 2024
• Source: TriHealth Inc.
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

A randomized controlled study will be conducted, with two arms. Postpartum women experiencing urinary retention will be randomized into one of the two following arms:

• Arm 1: Subjects will be exposed to vapor of peppermint oil

• Arm 2: Subjects will be exposed to vapor of placebo (mineral oil) Outcome variables include resolution of urinary retention, time to spontaneous urination, volume of spontaneous urination, frequency of urinary catheterization, and patient satisfaction.

Description:

The purpose of the study is to determine if the use of peppermint oil among postpartum women experiencing urinary retention will increase spontaneous urination and decrease the need for catheterization. A randomized controlled study will be conducted, with two arms. Subjects will be randomized into one of the two following arms:

• Arm 1: Subjects will be exposed to vapor of peppermint oil

• Arm 2: Subjects will be exposed to vapor of placebo (mineral oil) Outcome variables include resolution of urinary retention, time to spontaneous urination, volume of spontaneous urination, frequency of urinary catheterization, and patient satisfaction.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 100
• Est. completion date: March 30, 2026
• Est. primary completion date: January 30, 2026
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• 1. 18 years old or older 2. English speaking 3. Admitted to Bethesda North Mom Baby Unit 4. Postpartum 5. Experiencing urinary retention - defined as meeting at least one of the following criteria:

• More than 6 hours after delivery or foley catheter removal without being able to spontaneously void

• Symptomatic urinary retention without being able to spontaneously void

• Change in fundal height or position without being able to spontaneously void 6. Bladder scan showing bladder containing 400mL or more urine

Exclusion Criteria:

1. Allergy to peppermint

2. Asthma

3. Active herpes lesions

4. Seizure disorder

5. Not able to void in toilet (ex: requiring use of bed pan to void)

Related Conditions & MeSH terms

• Urinary Retention

Intervention

Other:
• Peppermint oil vapors
Subjects will be exposed to vapor of peppermint oil
• Mineral Oil
Subjects will be exposed to vapor of placebo (mineral oil)

Locations

Country	Name	City	State
United States	Bethesda North Hospital	Cincinnati	Ohio

Sponsors (1)

Lead Sponsor	Collaborator
TriHealth Inc.

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Percent of patients with urinary retention resolved	Urinary retention defined as: More than 6 hours after delivery or foley catheter removal without being able to spontaneously void; Symptomatic urinary retention without being able to spontaneously void; Change in fundal height or position without being able to spontaneously void More than 6 hours after delivery or foley catheter removal without voiding spontaneously; symptomatic urinary retention without being able to spontaneously void; or change in fundal height or position without being able to spontaneously void; Resolution of urinary retention will be achieved if patient spontaneously voids within 10 minutes after exposure to oil	10 minutes
Secondary	Time to spontaneous urination	Minutes until participant spontaneously voids	1 hour
Secondary	Volume of spontaneous urination	Volume of urine when participant spontaneously voids	1 hour
Secondary	Incidence of urinary catheterization	Whether participant requires urinary catheterization or not	1 hour
Secondary	Patient satisfaction	Patient rated satisfaction	1 hour