The Effect of Tamsulosin on Postoperative Urinary Retention

Status Terminated

Clinical Trial Summary

This is a double-blinded randomized controlled trial of perioperative use of tamsulosin to prevent postoperative urinary retention in female pelvic reconstructive surgery undergoing same-day discharge with an enhanced recovery after surgery protocol.

Clinical Trial Description

The primary objective is to determine the effect of Tamsulosin on same-day active voiding trial in women undergoing female pelvic reconstructive surgery with vaginal native tissue repair with same-day discharge planned. Duration of catheterization, postoperative urinary tract infection rates, patient level of satisfaction, Emergency Department (ED) visits and adverse events postoperatively will also be compared between women receiving Tamsulosin versus placebo. Patients will be offered participation in the study at their postoperative visit if they meet study criteria. Once consent is obtained, patients will be randomized to receive Tamsulosin 0.4 mg orally once daily or matching placebo capsules for a total of 10 days starting 5 days pre-operatively. ;

Study Design

Related Conditions & MeSH terms

Urinary Retention

Clinical Trial Details

NCT number	NCT04682366
Study type	Interventional
Source	Wake Forest University Health Sciences
Contact
Status	Terminated
Phase	Phase 4
Start date	October 19, 2021
Completion date	November 10, 2022

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT05538273` - Optimal Management of Urinary Catheter in Gyn Onc
Recruiting	`NCT05065255` - Study of the Criteria for Choosing Speedicath Catheters During the Initiation of Self-catheterization
Completed	`NCT04236596` - Pudendal Nerve Mapping Towards Improved Neuromodulation for Urinary Retention	N/A
Completed	`NCT05526651` - Improvement of Urinary Retention Symptoms With Electroacupuncture Therapy	N/A
Not yet recruiting	`NCT06070545` - The Effect of Modified Supine Position on Urinary Elimination After Percutaneous Coronary Intervention	N/A
Recruiting	`NCT03314025` - Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery	Phase 2
Recruiting	`NCT05439902` - Efficacy of Alpha-blockers (Tamsulosin) in the Treatment of Symptomatic Dysuria in Multiple Sclerosis in Women	N/A
Enrolling by invitation	`NCT05259800` - Peppermint Oil for Urinary Retention	N/A
Recruiting	`NCT06417346` - Comparison of Laparoscopic and Open Inguinal Hernia Repair in Elderly Patients	N/A
Completed	`NCT03296280` - Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
Completed	`NCT04715971` - Urinary Retention on an Acute Geriatric Hospitalisation Unit.
Completed	`NCT03302936` - Assessing Pyridium for Post-Sling Urinary Retention	Phase 4
Completed	`NCT02886143` - Effect of Active vs. Passive Voiding Trials on Time to Discharge, Urinary Tract Infection, and Urinary Retention	Phase 3
Completed	`NCT02749188` - Evaluation of Bladder Stimulation as a Noninvasive Technique of Urine Collection in Infant Who Have Not Acquired Walking	N/A
Completed	`NCT01284361` - Comparison of Two Intermittent Urinary Catheters	N/A
Completed	`NCT01220362` - Effects of Thoracic Epidural Analgesia and Surgery on Lower Urinary Tract Function: A Randomized, Controlled Study	N/A
Terminated	`NCT00804557` - Efficacy And Safety Of The Uro-Ease® Urinary Catheter During Clean Intermittent Catheterization	N/A
Terminated	`NCT00563654` - Randomized Trial Comparing Alfuzosin GITS 10 mg Daily With Placebo for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up	N/A
Terminated	`NCT00563485` - Randomized Trial Comparing Terazosin 5 mg Daily and Doxazosin GITS 4 mg Daily for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up	N/A
Terminated	`NCT03843073` - Connected Catheter- Safety and Effectiveness Study	N/A