Urinary Bladder Neoplasms Clinical Trial
Patients followed in the Foch Hospital Urology Department (Suresnes): Patients justifying a
prostatectomy.
- Patients justifying prostatectomy together with the bladder (radical cystectomy for
bladder cancer).
- Patients with benign prostate hyperplasia who justified a prostatectomy. Compare serum
sexual steroid concentrations and intra-tissue on healthy prostates and prostate
adenoma, assess concentrations intra-tissue sex steroids on cancer metastasis prostate
specific blood sample under study (30mL) will be performed preoperatively in Patients
followed in Foch Hospital Urology Department (Suresnes), and a Removal of a fragment of
prostate tissue or metastasis will be analyze.
Aim is to compare serum concentrations of sexual steroids and intra-tissue on healthy
prostates and prostate adenomas compared to concentrations measured in patients operated for
prostate cancer.
Steroids concentration will be determined using Gas chromatography-mass spectrometry. The
analyzed steroids are :
FSH :Mul/ml LH: mUI/ml SHBG: µg/ml BT: ng/ml TT: ng/ml DHT: ng/ml DHEA: ng/ml D5: ng/ml D4:
ng/ml E1: pg/ml E2 : pg/ml DHEA-S : µg/dl
;
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|---|---|---|---|
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|
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