UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones — UPURS  

Ureteral Stone Clinical Trial

Official title: Upfront vs Postponed Ureteroscopy (UPURS) Trial for Patient-centered Management of Symptomatic Obstructing Stones

Status Recruiting

Clinical Trial Summary

A prospective, non-blinded, randomized controlled trial studying the management of symptomatic ureteral stones. This study will compare upfront ureteroscopy vs observation and delayed intervention for patients presenting to the emergency department with a symptomatic ureteral stone.

Clinical Trial Description

Management of symptomatic ureteral stones is variable across the United States due to a lack of clear, patient-centered guidelines. For patients who do not meet criteria for emergent stenting, the decision to recommend upfront definitive treatment (ureteroscopy, ESWL) or medical expulsion therapy is influenced by factors such as practice setting, insurance status, and day of the week. This has resulted in health disparities and delays in care that disproportionately affect vulnerable patient populations.

For patients presenting to the emergency department with a symptomatic ureteral stone investigators will randomize into Group A: Upfront Ureteroscopy or Group B: Delayed intervention and observation. Both arms are considered standard of care for patients presenting with the above diagnosis. ;

Related Conditions & MeSH terms

• Ureteral Calculi
• Ureteral Stone
• Ureterolithiasis

• NCT number: NCT05715086
• Study type: Interventional
• Source: University of California, San Francisco
• Contact: Catherine Arevalo, BA
• Phone: 415-514-0918
• Email: catherine.arevalo@ucsf.edu
• Status: Recruiting
• Phase: N/A
• Start date: August 23, 2023
• Completion date: June 2024