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Clinical Trial Summary

Clinical trial to determine the efficacy (sensitivity and specificity) of Anchordx's urine DNA methylation/somatic mutation assay for detecting upper tract urothelial carcinoma compared to pathology in patients.


Clinical Trial Description

This is a prospective study that involves 8 centers in China and 490 participants. The test analyzes the DNA methylation/somatic mutation profiles of urothelial cancer-specific biomarkers non-invasively using urine specimens collected before invasive diagnosis/treatment. The efficacy (sensitivity and specificity) of the assay for detection of upper tract urothelial carcinoma is evaluated in comparison to pathology or cystoscopy. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04948528
Study type Observational
Source AnchorDx Medical Co., Ltd.
Contact Xu Chen, MD
Phone +86-13430306339
Email chenx457@mail.sysu.edu.cn
Status Recruiting
Phase
Start date September 1, 2020
Completion date December 31, 2023

See also
  Status Clinical Trial Phase
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Recruiting NCT05917158 - A Study of RC48-ADC Combined With JS001 For Postoperative Adjuvant Treatment of Upper Tract Urothelial Carcinoma Phase 2
Recruiting NCT02923557 - Prophylactic Intravesical Chemotherapy to Prevent Bladder Recurrence After Nephroureterectomy for Primary Upper Tract Urothelial Carcinoma Patients Phase 2
Recruiting NCT02969083 - Feasibility of Neo-adjuvant Versus Adjuvant Chemotherapy in Upper Tract Urothelial Carcinoma Phase 2
Recruiting NCT03544437 - Feasibility and Safety of Extraperitoneal Laparoscopic Extended Retroperitoneal Lymph Node Dissection at Time of Nephroureterectomy for Upper Tract Urothelial Carcinoma
Recruiting NCT03230201 - Lymph Node Dissection in High-risk UTUC(Upper Tract Urothelial Carcinoma) N/A
Recruiting NCT02740426 - Prophylactic Intravesical Chemotherapy to Prevent Bladder Recurrence After Diagnostic Ureteroscopy for Primary Upper Tract Urothelial Carcinoma Patients Phase 2
Active, not recruiting NCT03617003 - Treatment of Tumors in the Urinary Collecting System of the Kidney or Ureter Using a Light Activated Drug (WST11) Phase 1