Umbilical Cord Length Index for Prediction of Cord Abnormalities Before Delivery

Umbilical Cord Problem Clinical Trial

Official title:

Umbilical Cord Length Index as a New Ultrasonographic Method for Prediction of Cord Abnormalities Before Delivery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03604887
• Other study ID #: UCLI
• Status: Completed
• Start date: March 1, 2019
• Est. completion date: January 31, 2021

Study information

• Verified date: April 2021
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The umbilical cord plays an essential role in intrauterine life. It is the pathway between mother, placenta and fetus during pregnancy and delivery. Complete cord occlusion often leads to fetal demise, while intermittent occlusion has been associated with intrauterine brain damage. Compression and vasospasm in utero are important factors in fetal distress. Nuchal Umbilical Cord can be diagnosed antepartum using ultrasound, but the complications are unpredictable and unpreventable

Recruitment information / eligibility

• Status: Completed
• Enrollment: 300
• Est. completion date: January 31, 2021
• Est. primary completion date: December 1, 2020
• Accepts healthy volunteers: No
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Singleton pregnancy.

• Pregnant = 37 weeks gestation.

• Women who will accept to participate in the study

Exclusion Criteria:

• Preterm deliveries.

• Amniotic fluid abnormalities (oligohydramnios, polyhydramnios).

• Intrauterine growth retardation

• Early membrane rupture

• Women need urgent cesarean section.

• Multifetal gestation.

• Placenta previa.

• Fetuses with major congenital anomalies.

• Women with chronic maternal illness as hypertension

Related Conditions & MeSH terms

• Congenital Abnormalities
• Umbilical Cord Problem

Intervention

Diagnostic Test:
• ultrasonography
Ultrasound evaluation will be done with transducer abdominal probe. The amount of amniotic fluid and umbilical cord sections will be determined by evaluating the images obtained from the sagittal plane in the ultrasound evaluations in the 4 abdominal quadrants. When the anatomical structure of the umbilical cord is considered, it is folded in amniotic fluid. The folds appear as umbilical cord rings, side-by-side at the sagittal sections. Scoring of "umbilical cord length index" 1 point will be given for each quadrant where the umbilical cord was observed. 0.5 point will be given for each umbilical cord ring in one quadrant. Every quadrant will be evaluated in this manner, and the total score will be calculated.

Locations

Country	Name	City	State
Egypt	Assiut Faculty of Medicine	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The sensitivity of "Umbilical cord length index" in diagnosis of long and short umbilical cords.	Ultrasonographic scoring of umbilical cord length	15 minutes