Tumors Clinical Trial - Proton Radiotherapy for Recurrent Tumors

Status Completed

Clinical Trial Summary

The purpose of this study is to determine the feasibility of using proton radiotherapy for reirradiation of recurrent malignancies.

Clinical Trial Description

Patients will be stratified by treatment site (Head and Neck, Thorax, Abdomen, Pelvis, Extremities) and by treatment volume (low volume, high volume) for a total of 10 strata. This study will be done in two phases. In the first phase, feasibility will be established using the primary objectives set below. The second phase will begin no earlier than 90 days after the last patient in the initial phase has completed treatment in each strata and once feasibility has been verified. The secondary objectives will serve as the objectives for the second phase of the study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01126476
Study type	Interventional
Source	Abramson Cancer Center of the University of Pennsylvania
Contact
Status	Completed
Phase	N/A
Start date	February 2010
Completion date	April 2020

View Details

See also
Status	Clinical Trial	Phase
Suspended	`NCT01562626` - Phase I/II Study of APS001F With Flucytosine and Maltose in Solid Tumors	Phase 1/Phase 2
Completed	`NCT00435669` - A Phase I Study to Determine Absorption, Distribution, Metabolism, and Elimination of a Single Radiolabeled Dose of Brivanib (BMS-582664)	Phase 1
Completed	`NCT00375245` - Rapamycin With Grapefruit Juice for Advanced Malignancies	Phase 1
Completed	`NCT00372437` - A Phase I/II Study of MGCD0103 (MG-0103) in Combination With Gemcitabine	Phase 1/Phase 2
Completed	`NCT00400023` - A Phase 1, Open-Label, Randomized, Cross-Over, Pharmacokinetic Study Evaluating the Effect of S-1 on Advanced Solid Tumors	Phase 1
Completed	`NCT00395434` - Safety Study of Increasing Doses of Combretastatin in Combination With Bevacizumab (Avastin) in Patients With Advanced Solid Tumors	Phase 1
Completed	`NCT00410696` - Pegfilgrastim Versus Filgrastim After High-dose Chemotherapy	Phase 2
Recruiting	`NCT00553033` - Laparoscopic Liver Resection	N/A
Completed	`NCT00248404` - NB1011 Administered by Continuous Infusion in Cancers That Overexpress Thymidylate Synthase (TS)	Phase 1/Phase 2
Completed	`NCT00222443` - Pilot Study Combining Temozolomide, Oncovin, Camptosar and Oral Antibiotic in Children and Adolescents With Recurrent Malignancy	Phase 1
Completed	`NCT00207103` - MAD in Cancer Patients: Safety of BMS-582664 in Patients With Advanced or Metastatic Solid Tumors	Phase 1
Terminated	`NCT03251924` - A Dose Escalation and Combination Immunotherapy Study to Evaluate BMS-986226 Alone or in Combination With Nivolumab or Ipilimumab in Patients With Advanced Solid Tumors	Phase 1/Phase 2
Recruiting	`NCT05103969` - Cohort of Tumors With POLE/D1 Mutation
Completed	`NCT00446446` - PRISM (Panitumumab Regimen In Second-line Monotherapy of Head and Neck Cancer)	Phase 2
Completed	`NCT02275910` - Phase 1 Study of E7090 in Subjects With Solid Tumor	Phase 1
Terminated	`NCT02271516` - to evaluate188Re-BMEDA-liposome in Patient With Primary Solid Tumor in Advanced or Metastatic Stage	Phase 1
Completed	`NCT01448759` - Evaluation of Plasma Alcohol Concentration in Patients Receiving Paclitaxel or Docetaxel	N/A
Terminated	`NCT01081808` - Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors	Phase 1
Completed	`NCT00398814` - Phase I Study of Perifosine + Sorafenib for Patients With Advanced Cancers	Phase 1
Completed	`NCT00389480` - Study of AR-67 (Formerly DB-67) in Adult Patients With Refractory or Metastatic Solid Malignancies	Phase 1