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Clinical Trial Summary

The aim of this study was to evaluate the progression time and efficacy of brain tumors in patients with brain metastases from HER2-positive breast cancer treated with Pyrrolidine and Capecitabine combined with brain radiotherapy.


Clinical Trial Description

Brain metastases are very common in HER2-positive breast cancer patients. The vast majority of patients with metastatic brain tumors are in advanced stages of the disease. If not treated in time, the natural course of the disease is extremely short. At present, the main treatment of brain metastases from breast cancer is radiotherapy, combined with chemotherapy and targeted therapy drugs. On the basis of previous clinical studies, the aim of this study was to explore the efficacy and safety of combined brachytherapy with Pyrrotidine and Capecitabine in patients with brain metastases from HER2-positive breast cancer, in order to provide a new, safer and more effective treatment for patients with brain metastases from breast cancer. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04767828
Study type Interventional
Source Tianjin Medical University Cancer Institute and Hospital
Contact Jing Wang, MD
Phone 13920762182
Email wj62182@126.com
Status Recruiting
Phase Phase 4
Start date May 1, 2020
Completion date June 2022

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