Tricuspid Regurgitation Clinical Trial
Official title:
Valutazione Del Rimodellamento Delle Camere Destre Dopo Trattamento Transcatetere Edge-to-edge Dell'Insufficienza Tricuspidale Severa
In the recent years, secondary tricuspid regurgitation (STR) has gained interest due to its high prevalence and impact on outcomes. Transcatheter tricuspid valve replacement or repair represents novel and less invasive alternatives to surgery and has shown early promising results. Treatment options mimic surgical techniques such as leaflet approximation, direct annuloplasty, and heterotopic caval valve implantation, as well as not yet commercially available transcatheter TV replacement systems using orthotopic valve implantation. (5) Among leaflet approximation techniques, the Tricuspid transcatheter edge-to-edge repair (T-TEER) using the TriClip™ (Abbott Vascular, Santa Clara, CA, USA) or leaflet approximation with the PASCAL systems (Edwards Lifesciences, Irvine, CA, USA) are approved in Europe for minimally invasive TV repair.The purposes of the present study are: i. to use 3DE and CCT to evaluate the effect of T-TEER on the geometry and function of the right heart chambers in patients with STR; ii. to identify the predictors of procedural success potentially related to features of both right chambers geometry and TR jet; iii. to compare the accuracy of 3DE assessment of the right ventricle, the right atrium, and the tricuspid annulus, with the same parameters obtained by CCT, in the setting of T-TEER; and iv. to assess patients' outcome.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05434507 -
Feasibility Study of Treating Tricuspid Regurgitation With K-ClipTM Transcatheter Annuloplasty System
|
N/A | |
| Completed |
NCT03144024 -
Comparison of Rigid Annuloplasty Ring With a Band in the Correction of Secondary Tricuspid Insufficiency
|
N/A | |
| Enrolling by invitation |
NCT05825898 -
Outcome of Patients With Severe Functional TR According to Medical, Transcatheter or Surgical Treatment
|
||
| Completed |
NCT05836493 -
Very Long-term (>15 Years) Results of Tricuspid Valve Repair.
|
||
| Enrolling by invitation |
NCT06033274 -
Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment
|
||
| Recruiting |
NCT05671640 -
Feasibility Study of the DragonFly-T System for Severe Tricuspid Regurgitation
|
N/A | |
| Recruiting |
NCT06027307 -
Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation
|
Phase 3 | |
| Terminated |
NCT04665583 -
Prehab Prior to Undergoing Tricuspid Intervention
|
||
| Recruiting |
NCT06307262 -
European Registry of Transcatheter Repair for Tricuspid Regurgitation
|
||
| Completed |
NCT02981953 -
TRI-REPAIR: TrIcuspid Regurgitation RePAIr With CaRdioband Transcatheter System
|
N/A | |
| Recruiting |
NCT04433065 -
TTVR Early Feasibility Study
|
N/A | |
| Not yet recruiting |
NCT05556460 -
Safety and Effectiveness Study of DragonFly-T System for Severe Tricuspid Regurgitation
|
N/A | |
| Recruiting |
NCT05667519 -
Prevention of Pacemaker Lead Induced Tricuspid regurgitAtion by Transesophageal eCho guidEd Implantation (PLACE)
|
N/A | |
| Recruiting |
NCT04653428 -
German Registry for Transcatheter Tricuspid Valve Interventions
|
||
| Recruiting |
NCT05179616 -
Pforzheim Tricuspid Valve Registry - Outcomes of Percutaneous Tricuspid Valve Repair
|
||
| Completed |
NCT02644616 -
The Safety and Efficacy of Tolvaptan for Patients With Tricuspid Regurgitation and Right Heart Failure After Left Heart Valves Replacement
|
Phase 4 | |
| Recruiting |
NCT05328284 -
PASCAL for Tricuspid Regurgitation - a European Registry
|
||
| Completed |
NCT02675244 -
Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery
|
N/A | |
| Recruiting |
NCT05436028 -
A Study to Evaluate the Safety and Performance of LuX-Valve Plus System for Tricuspid Replacement
|
N/A | |
| Completed |
NCT01093001 -
Tricuspid Regurgitation Study
|
Phase 4 |