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Clinical Trial Summary

The main objective of this study is to provide data on the efficacy profile of different doses of oxfendazole when used in Trichuris trichiura infection. The drug will be also be examined for efficacy against other common nematodes encountered in man (Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus). The study will also provide data on the safety and tolerability of the oxfendazole in patients.


Clinical Trial Description

This is an assessor blind, randomized, comparative study in adult patients with proven intestinal infection with Trichuris trichiura to be conducted as a field study. Patients meeting the study entry criteria will receive either 6 mg/kg or 15 mg/kg or 30 mg/kg of oxfendazole as a single oral dose, three single doses of oxfendazole on consecutive days, or albendazole 400mg as a single oral dose. Stool samples will be obtained and examined prior to treatment and at 7, 14 and 21 days after treatment. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03435718
Study type Interventional
Source Oxfendazole Development Group
Contact ellen codd, MS
Phone 484 557 3831
Email ellen.codd@oxfendazoledevelopmentgroup.org
Status Not yet recruiting
Phase Phase 2
Start date July 2024
Completion date October 2026

See also
  Status Clinical Trial Phase
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