Cognitive Behavioral Group Therapy for Trichotillomania (Hair Pulling Disorder)

Trichotillomania Clinical Trial

— NorTriP  

Official title:

The Norwegian Trichotillomania Project

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02747771
• Other study ID #: 2013/632
• Status: Recruiting
• Start date: January 1, 2013
• Est. completion date: December 31, 2026

Study information

• Verified date: March 2024
• Source: Oslo University Hospital
• Contact: Benjamin Hummelen, Ph.D., M.D.
• Phone: +4795741039
• Email: uxbeum[@]ous-hf.no
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study aims at evaluating the effectiveness of group-based cognitive behavioral therapy for trichotillomania at three clinical sites in Norway.

Description:

The Norwegian Trichotillomania Project is a multicenter study that aims at evaluating the effectiveness of behavioral group therapy for TTM, i.e., ACT (Acceptance and commitment therapy) enhanced habit reversal training (ACT-enhanced HRT).

Participants are adults or adolescents (16 year or older) who fulfill criteria for TTM according to DSM-IV. Inclusion started in January 2013 and will be completed by Mai 2016. Treatment is delivered at three treatment sites in Norway; in Kristiansand, Oslo, and Trondheim. Treatment is manualized, following the manual of Twohig and Woods, and consists of ten group sessions of three hours delivered at consecutive weeks, and two or three booster sessions during the first year after treatment.

Treatment outcome is evaluated by three outcome measures; the Massachusetts General Hospital

• Hairpulling Scale (self-report); the National Institute of Mental Health Trichotillomania Severity Scale (clinical interview, conducted by independent evaluators); and the Clinical Global Impression Scale for TTM. Outcome is measured at three points in time; at baseline, at the end of treatment, and at one-year follow-up. Mixed models procedures in SPSS is used to analyze longitudinal data.

The first paper will be written on patients admitted to treatment from January 2013 to September 2014, and includes 53 patients (49 women and four men). By January 2016, fifty-one patients (96%) had participated in the one-year follow-up evaluation.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 150
• Est. completion date: December 31, 2026
• Est. primary completion date: April 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 16 Years to 67 Years

Eligibility

• Inclusion Criteria:

• Clinical diagnosis of Trichotillomania

• Age between 16 and 67

• Exclusion Criteria:

• schizophrenia spectrum disorder

• substance addiction

• severe antisocial, schizotypal, or paranoid personality disorder

• severe eating disorder,

• ongoing suicidal ideation

• pervasive developmental disorder

• mental retardation and severe sequelae after brain injury.

Related Conditions & MeSH terms

• Trichotillomania

Intervention

Behavioral:
• Cognitive behavioral therapy
10 sessions Group therapy during 10-12 weeks. The first three sessions focus on habit reversal training, the fourth to sixth session on acceptance and commitment therapy and the last four sessions aims at integrating the two approaches.

Locations

Country	Name	City	State
Norway	Oslo University Hospital	Oslo

Sponsors (5)

Lead Sponsor	Collaborator
Oslo University Hospital	Sorlandet Hospital HF, St. Olavs Hospital, Texas A&M University, University of Michigan

Country where clinical trial is conducted

Norway, 

References & Publications (5)

Houghton DC, Capriotti MR, De Nadai AS, Compton SN, Twohig MP, Neal-Barnett AM, Saunders SM, Franklin ME, Woods DW. Defining treatment response in trichotillomania: a signal detection analysis. J Anxiety Disord. 2015 Dec;36:44-51. doi: 10.1016/j.janxdis.2 — View Citation

Keuthen NJ, Rothbaum BO, Fama J, Altenburger E, Falkenstein MJ, Sprich SE, Kearns M, Meunier S, Jenike MA, Welch SS. DBT-enhanced cognitive-behavioral treatment for trichotillomania: A randomized controlled trial. J Behav Addict. 2012 Sep;1(3):106-14. doi: 10.1556/JBA.1.2012.003. — View Citation

Stein DJ, Garner JP, Keuthen NJ, Franklin ME, Walkup JT, Woods DW. Trichotillomania, stereotypic movement disorder, and related disorders. Curr Psychiatry Rep. 2007 Aug;9(4):301-2. doi: 10.1007/s11920-007-0036-4. — View Citation

Stein DJ, Grant JE, Franklin ME, Keuthen N, Lochner C, Singer HS, Woods DW. Trichotillomania (hair pulling disorder), skin picking disorder, and stereotypic movement disorder: toward DSM-V. Depress Anxiety. 2010 Jun;27(6):611-26. doi: 10.1002/da.20700. — View Citation

Woods DW, Wetterneck CT, Flessner CA. A controlled evaluation of acceptance and commitment therapy plus habit reversal for trichotillomania. Behav Res Ther. 2006 May;44(5):639-56. doi: 10.1016/j.brat.2005.05.006. Epub 2005 Jul 22. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in National Institute of Mental Health Trichotillomania Severity Scale (NIMH-TSS)	clinical interview	baseline, 12 weeks, 12 months
Primary	Change in Massachusetts General Hospital - Hairpulling Scale (MGH-HS)	self-report	baseline, 12 weeks, 12 months
Secondary	Change Patient Health Questionnaire-9 (PHQ-9)	self-report depressive symptoms	baseline, 12 weeks, 12 months
Secondary	Change General Anxiety Disorder Scale (GAD-7)	self-report anxiety symptoms	baseline, 12 weeks, 12 months
Secondary	Change Metacognition Questionnaire (MCQ-30)	self-reported metacognitions	baseline, 12 weeks, 12 months
Secondary	Change in Acceptance and Action Questionnaire for Trichotillomania	self-report	baseline, 12 weeks, 12 months