Rapid Acting Transcranial Magnetic Stimulation

Status Recruiting

Clinical Trial Summary

This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for treatment-resistant depression. In a double-blind, randomized, sham-controlled fashion, half the participants will receive accelerated theta-burst stimulation while half will receive sham treatment.

Clinical Trial Description

Repetitive transcranial magnetic stimulation (rTMS) is an established therapy for treatment-resistant depression. The approved method for treatment is 10Hz stimulation for 40 min over the left dorsolateral prefrontal cortex (L-DLPFC). This methodology has been effective in real world situations. The limitations of this approach include the duration of the treatment (approximately 40 minutes per treatment session, 5 days per week, for 4-8 weeks). Recently, we have pursued modifying the treatment parameters to reduce treatment times with an accelerated treatment paradigm with great preliminary success. This study aims to further study our accelerated protocol and examine changes in neuroimaging biomarkers. ;

Study Design

Related Conditions & MeSH terms

Depressive Disorder, Treatment-Resistant
Treatment Resistant Depression

Clinical Trial Details

NCT number	NCT04739969
Study type	Interventional
Source	Stanford University
Contact	Nick Bassano, MSW
Phone	650-736-2233
Email	nbassano@stanford.edu
Status	Recruiting
Phase	N/A
Start date	June 15, 2021
Completion date	December 2025

View Details

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