Colchicine Has Anti-diabetic Effect

Treatment Adherence Clinical Trial

Official title:

Colchicine Has Anti-diabetic Effect and May be an Option for Type 2 Diabetes Management

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04377321
• Other study ID #: ymodmenna@gmail.com
• Status: Completed
• Start date: October 10, 2019
• Est. completion date: May 2, 2020

Study information

• Verified date: May 2020
• Source: Ministry of Health and Population, Egypt
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Colchicine has antidiabetic effect and may be an option for type 2 diabetes management

Description:

Observational cohort prospective study with following of 150 newly diagnosed type 2 diabetes patients who were in 3 groups, had been monitored in a private clinic, each group 50 patients number, with 30 females and 20 males after written consent from all patients. The ages of all patients were between 35 and 55 years.

The aim of this study was to evaluate colchicine effect on A1C of newly diagnosed type2 diabetes compared to the metformin and control group on diet only.

The first group patients received colchicine 0.5twice daily for 6 months, the second group received metformin 1gm twice daily, the third group patients were on diet only. During the period of treatment, the investigators followed the patients if there were side effects of the drugs used. No side effects were monitored during the period of treatment except for gastric upset in some patients using metformin

Recruitment information / eligibility

• Status: Completed
• Enrollment: 150
• Est. completion date: May 2, 2020
• Est. primary completion date: May 1, 2020
• Gender: All
• Age group: 35 Years to 55 Years

Eligibility

Inclusion Criteria:

• type 2 diabetes newly diagnosed age 35- 55 years

Exclusion Criteria:

• severe anemia hypothyroidism and hyperthyroidism moderate to severe liver or kidney disease

Related Conditions & MeSH terms

• Treatment Adherence

Intervention

Drug:
• Colchicine Tablets
colchicine tabletes for 6 months

Locations

Country	Name	City	State
Egypt	Mahmoud Younis	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Ministry of Health and Population, Egypt

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	colchicine for treatment of type diabetes patients	colchicine tablets .5 mg twice daily for 6 months	6 months