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Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department

Trauma Clinical Trial

Official title:
Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department: A Prospective Randomized Controlled Study

Clinical Trial Summary

This study evaluates the addition of a lidocaine patch to ibuprofen in the treatment of acute musculoskeletal pains. Half of the participants will get only ibuprofen for their pain, while other half will receive lidocaine patch plus the ibuprofen. After addition of the pain medications, the participants will be followed for their pain scores and return visits.

Clinical Trial Description

Ibuprofen and other nonsteroidal antiinflammatory pain medications have been traditionally used for relief of mild to moderate acute musculoskeletal pains. However, if this medication did not work, a different modality for pain control would be added to the original regimen. In recent times, lidocaine patch has been introduced as a separate modality for pain control. This medication is thought to help by selectively inhibiting voltage-gated sodium channels in nociceptors involved in pain response. Given the separate modality, it would be prudent to see whether the addition of lidocaine patch to the ibuprofen would help relieve the pain more so than the antiinflammatory-only regimen. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03571737
Study type Interventional
Source East Carolina University
Contact
Status Completed
Phase Phase 3
Start date June 23, 2018
Completion date January 30, 2021
View Details
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