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NCT00192907 Clinical Trial

Inflammation and Infection in Trauma, Role in Posttraumatic Complications

Trauma Clinical Trial

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT00192907
Other study ID # KF 01-160/02 Main
Secondary ID
Status Active, not recruiting
Phase N/A
First received September 12, 2005
Last updated September 16, 2005
Start date March 2003
Est. completion date September 2005

Study information
Verified date September 2005
Source Rigshospitalet, Denmark
Contact n/a
Is FDA regulated No
Health authority Denmark: Danish Dataprotection Agency
Study type Observational

Clinical Trial Summary

The purpose of this study is to investigate the relationship between trauma, the immune system, biochemical changes in the first 24 h and subsequent complications and mortality

Description:

The immune system plays a role in the development of complications after severe trauma, but we do not know how. Equally, biochemical changes measured in the blood after trauma (eg. bloodglucose, GC-globulin, coagulation parameters etc.) may predict the prognosis and the degree of complcations. Two significant complications are infection and organ failure, which may prolong hospitalisation and increase mortality.

In the study we collected samples from blood and body surfaces to determine changes in cytokines, biochemistry, bacterial flora, and subsequent complications. We compare the changes in between groups of the cohort.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 380
Est. completion date September 2005
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Clinical suspicion of multiple trauma

- Age >/= 18 years

- Direct referral from scene of accident

Exclusion Criteria:

- Major burn injury

- HIV positiv

- Pregnancy

Study Design

Observational Model: Defined Population, Time Perspective: Longitudinal

Related Conditions & MeSH terms

Locations
Country Name City State
Denmark Rigshospitalet, Copenhagen University Hospital DK-2100 Copenhagen

Sponsors (1)
Lead Sponsor Collaborator
Rigshospitalet, Denmark

Country where clinical trial is conducted

Denmark, 

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