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Prevention of Severe Acute Graft-versus-host Disease in Pediatric Patients Using a daGOAT Model

Transplant-Related Disorder Clinical Trial

Official title:
A Prospective, Single-arm Clinical Trial of Prevention of Severe Acute Graft-versus-host Disease After Pediatric Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation Using a daGOAT Model

Clinical Trial Summary

To evaluate the efficacy and safety of ruxolitinib for prophylactic therapy of child patients who are predicted to have a high risk for developing severe acute graftversus-host disease (aGVHD) by the dynamic aGVHD Onset Anticipation Tianjin (daGOAT) model.

Clinical Trial Description

This study aims to prospectively evaluate the use of the daGOAT model in real-world clinical settings at the Institute of Hematology, Chinese Academy of Medical Sciences (IHCAMS). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05599256
Study type Interventional
Source Institute of Hematology & Blood Diseases Hospital
Contact Xueou Liu, PhD
Phone 022-23909051
Email liuxueou@ihcams.ac.cn
Status Recruiting
Phase Phase 2
Start date February 9, 2023
Completion date December 1, 2025
View Details
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