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Tracheoesophageal Fistula clinical trials

View clinical trials related to Tracheoesophageal Fistula.

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NCT ID: NCT03730454 Recruiting - Esophageal Atresia Clinical Trials

Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair

TEF
Start date: May 11, 2018
Phase: N/A
Study type: Interventional

This trial will compare the effectiveness of two common surgical practices for Type C esophageal atresia repair: esophageal atresia (EA) with distal tracheoesophageal fistula (TEF). Infants with EA/TEF requiring surgical intervention will be recruited. Subjects will be randomized to either repair with or without transanstomotic tube (TT) during esophageal anastomosis creation. Primary outcome is symptomatic anastomotic stricture development requiring dilation within 12 months.

NCT ID: NCT03455881 Recruiting - Tracheal Stenosis Clinical Trials

Phenotypic and Genetic Assessment of Tracheal and Esophageal Birth Defects in Patients

TED
Start date: March 28, 2018
Phase:
Study type: Observational

The investigators propose a preliminary study performing exome sequencing on samples from patients and their biologically related family members with tracheal and esophageal birth defects (TED). The purpose of this study is to determine if patients diagnosed with TED and similar disorders carry distinct mutations that lead to predisposition. The investigators will use advanced, non-invasive magnetic resonance imaging (MRI) techniques to assess tracheal esophageal, lung, and cardiac morphology and function in Neonatal Intensive Care Unit (NICU) patients. MRI techniques is done exclusively if patient is clinically treated at primary study location and if patient has not yet had their initial esophageal repair.

NCT ID: NCT03026491 Completed - Chewing Problem Clinical Trials

Chewing in Children With Repaired Esophageal Atresia-tracheoesophageal Fistula

Start date: January 1, 2017
Phase: N/A
Study type: Observational

The investigators aim to evaluate chewing function in children with repaired esophageal atresia-tracheoesophageal fistula (EA-TEF). Patients with repaired EA-TEF will be evaluated for age, sex, type of atresia. Each child will be required to bite and chew a standardized biscuit. Chewing function will be scored with the Karaduman Chewing Performance Scale (KCPS). The International Dysphagia Diet Standardisation Initiative (IDDSI) will be used to determine the tolerated food texture of children.

NCT ID: NCT02364843 Terminated - Clinical trials for Diaphragmatic Hernia

A Physiological Study to Determine the Enteral Threonine Requirements in Infants Aged 1 to 6 Months

INFORALTHR
Start date: February 2016
Phase: N/A
Study type: Interventional

This is the 5th in a series of physiological studies to determine the amino acid requirements of infants. There have been 4 studies to determine tyrosine, methionine, threonine and lysine requirements in infants when they are fed by parenterally (intravenously). Due to the new requirements of Health Canada for preparation of parenteral solutions, the investigators are starting the phase of the study that determines the enteral (oral) intake of threonine in 1 - 6 mo infants in the interim.

NCT ID: NCT02033772 Completed - Clinical trials for Congenital Diaphragmatic Hernia

Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic Surgery

Start date: August 2013
Phase: N/A
Study type: Observational

The study is primarily a descriptive study examining the physiological, ventilatory, surgical, and recovery effects of patients ≤ 6 months of age who undergo thoracoscopic surgery and to determine the accuracy of transcutaneous CO2 (TC-CO2) and end-tidal CO2 (ET-CO2) during high frequency oscillatory ventilation (HFOV) and thoracoscopic procedures.

NCT ID: NCT01467245 Completed - Clinical trials for Congenital Diaphragmatic Hernia

Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood Gases

CO2
Start date: August 2009
Phase: N/A
Study type: Interventional

This is a pilot randomised controlled trial comparing open versus thoracoscopic surgery for repair of oesophageal atresia with tracheo-oesophageal fistula or congenital diaphragmatic hernia in neonates. Thoracoscopic surgery involves insufflation of carbon dioxide into the thoracic cavity and may therefore cause hypercapnia and acidosis.

NCT ID: NCT01287312 Recruiting - Clinical trials for Tracheo Esophageal Fistula

Trichloroacetic Acid for Endoscopic Tracho-esophageal Fistula Repair

Start date: January 2011
Phase: N/A
Study type: Interventional

Today Endoscopic repair of recurrent Tracheesophageal fistula (TEF) is a safe procedure. Using Trichlosiacetic acid 50% (TCA) for endoscopic aplication of the fistula was reported with a good results ( 4 cases). There were no serious advers effects. The investigators want to use also TCA 50% for endoscopic repair in children with recurrent TEF.

NCT ID: NCT01153061 Terminated - Clinical trials for Acquired Tracheo-esophageal Fistula

Endoscopic Closure of Tracheoesophageal Fistulas With Occluder Device

TEFGoreHelex
Start date: June 2010
Phase: Phase 4
Study type: Interventional

Endoscopic closure of tracheoesophageal fistulas with a device used for closure of cardiac septal defects.