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Study on Baroreceptor Function in Relation to Orthostatic Blood Pressure Regulation After Hip Surgery

Total Hip Replacement Clinical Trial

Official title:
Baroreceptor Function and Inflammation in Relation to Orthostatic Intolerance During Early Mobilization After Elective Hip Arthroplasty

Clinical Trial Summary

The purpose of this observational study is to evaluate the baroreceptor function in relation to surgical inflammation and orthostatic intolerance after elective hip arthroplasty.

The main hypothesis is that baroreceptor function is attenuated after surgery and related to surgical inflammation.

Clinical Trial Description

Orthostatic intolerance and hypotension is prevalent during early mobilization after major surgery.

This observational study aims to evaluate the baroreceptor function during using a standardized evaluation protocol before, 6- and 24 hours after elective primary unilateral hip-arthroplasty.

The study hypothesis is that baroreceptor function as expressed by the valsalva ratio is attenuated after surgery and related to surgical inflammation. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01866787
Study type Observational
Source Rigshospitalet, Denmark
Contact Øivind Jans, M.D
Email oeivind.jans@regionh.dk
Status Recruiting
Phase N/A
Start date January 2013
Completion date December 2015
View Details
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