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Torticollis clinical trials

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NCT ID: NCT03270189 Terminated - Clinical trials for Nervous System Diseases

Effect of the Visual Information Change in Functional Dystonia

PRISMADYS
Start date: September 18, 2017
Phase: N/A
Study type: Interventional

Cervical dystonia occurring only during the writing task is a rare form for which there is no established treatment. Many authors agree that alteration of sensory integration is associated with dystonia. Similar disturbances in the integration of oculomotor information could have a role in cervical dystonia forms involving visuo-cervico-manual coordination such as handwriting. We hypothesize that orthoptic treatment by wearing prisms when writing (i) will reduce the abnormal posture of the head occurring whilst writing and remove the associated nuchal pain; (ii) the correction after a period of systematic wearing of the prisms during handwriting tasks will have a sustainable effect allowing to keep a normal head position after the suppression of the prisms.

NCT ID: NCT02907801 Terminated - Clinical trials for Congenital Muscular Torticollis

Perception-Action Approach Intervention for Infants With Congenital Muscular Torticollis

P-AA
Start date: January 10, 2017
Phase: N/A
Study type: Interventional

Infants with congenital muscular torticollis (CMT) display postural and functional asymmetry that interferes with their development. The use of the Perception-Action Approach (P-AA) intervention in infants with CMT is supported by a single case report and needs to be researched further to determine its efficacy. This study will investigate the immediate effects of the P-AA intervention on habitual head deviation from midline, active head rotation range of motion, and functional use of both sides of the body in infants with CMT. The participants will be 3 infants with CMT, aged birth to 9 months. A randomized, nonconcurrent A-B multiple baseline design across subjects will be used. The intervention phase will include 5 daily PT sessions, with outcome data collected at the end of each session. It is hypothesized that improvements on all outcome measures will be documented upon the initiation of the P-A Approach intervention, with the most substantial change expected in habitual head deviation from midline measured by still photography.

NCT ID: NCT02877836 Terminated - Spasticity Clinical Trials

Functional MRI and DTI in the Preoperative Assessment of Dystonia

IRMF-DIFF
Start date: September 19, 2014
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the organization of the motor circuit in a group of patients suffering from dystonia compared with a group of healthy controls. Deep Brain stimulation is a functional neurosurgery technique consisting in neuromodulation of the motor circuit that has been applied to dystonia. The efficiency of this technique depends on the relative preservation of the function and the structure of the motor network . The assessment of neuronal circuit by advanced techniques of functional neuroimaging in this study might contribute to expand our understanding of the abnormalities in motor circuit activation and the integrity of CNS structure underlying dystonia. This study might contribute therefore to the refinement of Deep brain stimulation indications and techniques in complex dystonia syndromes

NCT ID: NCT02837185 Terminated - Clinical trials for Cervical Dystonia, Primary

Effects of Botulinum Toxin on Muscle and Brain Activity

Start date: August 2016
Phase: N/A
Study type: Interventional

This study will look into the effects of Botulinum Toxin in patients with primary cervical dystonia. The effects will be determined by neck muscle activity measurements and brain function activity measurements. The goal of the study is to try to identify markers of the effects of Botulinum toxin.

NCT ID: NCT02824848 Terminated - Clinical trials for Congenital Muscular Torticollis

Perception-Action Approach vs. Passive Stretching for Infants With Congenital Muscular Torticollis

Start date: August 4, 2016
Phase: N/A
Study type: Interventional

Congenital muscular torticollis (CMT) results from tightness of neck musculature that causes the infant to tilt the head to one side and turn it to the other side. Infants with CMT also show unequal use of both sides of the body for movement and play. In this randomized clinical trial, researchers will compare two physical therapy (PT) treatment methods, passive stretching and Perception-Action (P-A) Approach, in their effects on head position and use of both sides of the body in infants with CMT. Behavior demonstrated during PT sessions by infants in the two groups will be also compared. Thirty-six infants with CMT will be randomly assigned to a passive stretching group or a P-A Approach group. The infants in both groups will attend 5 weekly PT sessions, including the initial evaluation, 3 subsequent weekly sessions, and a re-evaluation session. At visits 1 and 5, each infant's habitual head position, the ability to turn the head to both sides, muscle strength on both sides of the neck, motor development, and use of both sides of the body for movement and play will be assessed. Each infant's behavior exhibited during therapy will be assessed at visits 2-4. Results obtained from the two groups will be compared. It is hypothesized that: 1. There will be significant gains achieved by both intervention groups between the initial and final assessments on the following outcome measures: 1. Still photography 2. Arthrodial goniometry used to assess active head rotation to both sides 3. The Muscle Function Scale (MFS) used to assess neck muscle strength 4. The Alberta Infant Motor Scale (AIMS) used to assess motor development 2. There will be no significant difference between the groups on the above listed measures after the intervention is completed. 3. The P-A Approach group will achieve greater gains than the passive stretching group between the initial and final assessments on the Functional Symmetry Observation Scale (FSOS) used to assess the use of both sides of the body for movement and play 4. The P-A Approach group will demonstrate higher Therapy Behavior Scale (TBS) scores than the passive stretching group assigned based on participants' behavior demonstrated during PT intervention sessions

NCT ID: NCT00879450 Terminated - Torticollis Clinical Trials

Evaluating the Impact of a New Complement to Physiotherapy Intervention for Positional Torticollis in Infants

Start date: May 2009
Phase: N/A
Study type: Interventional

Children with a torticollis are usually referred for physiotherapy where they are evaluated, and given exercises as well as education to treat the condition. This study is being done in order to compare 2 methods of sharing information with parents of children with torticollis.

NCT ID: NCT00760318 Terminated - Cervical Dystonia Clinical Trials

Keppra for Cervical Dystonia

Keppra
Start date: November 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate if there is an improved response in CD symptoms when Keppra is used as adjunctive therapy to Botox.

NCT ID: NCT00432341 Terminated - Clinical trials for Spasmodic Torticollis

Efficacy and Safety of Two Different Botulinum Toxin Type A Treatments for Moderate to Severe Cervical Dystonia

Start date: June 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare two types of botulinum toxin type A to treat the involuntary muscle contractions in the neck