Tooth, Impacted Clinical Trial
Official title:
Effect of Racemic Ketamine on Pain in Females and Males After Surgical Removal of Third Molars
The purpose of the study is to determine whether equal subanesthetic doses of racemic ketamine is equally effective on females and males after surgical removal of third molars
Ketamine is assumed to be a NMDA receptor antagonist which provides analgesia from acute
postoperative pain(and other types of pain) subanesthetic doses. Gender differences in
ketamine analgesia are not known. This placebo-controlled,randomised, parallel group study
investigates the analgesic dose-response effect of ketamine in subanesthetic doses in female
and male patients following surgical removal of third molars.
Comparisons: Placebo and ketamine in females and males.
;
Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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