Tooth Extraction Clinical Trial
Official title:
The Effect of Alveolar Ridge Preservation After Tooth Extraction in the Posterior Maxilla: A Randomized, Split-Mouth, Controlled Trial.
This study is designed to assess the effects of Alveolar Ridge Preservation (ARP) after tooth extraction compared to extraction alone in the posterior maxilla. The results of this study will demonstrate if the use of ARP reduces alveolar ridge resorption at 6 months post extraction in the posterior maxilla region.
Fifteen subjects requiring extraction of one posterior tooth in the right maxilla and one posterior tooth in the left maxilla will be considered for enrollment. Subjects who meet the inclusion and exclusion criteria will be randomized to receive alveolar ridge preservation on one side of the maxilla and only an extraction on the other side of the maxilla. Extraction of the failing teeth will be performed atraumatically; a mucoperiosteal flap will not be employed. After removal of the tooth, the alveolus will be meticulously debrided and cleaned. In the test site, the socket will be filled with xenograft and a collagen membrane. In the control site, no graft material or collagen membrane will be used. Clinical measurements, standardized peri-apical radiographs and Cone Beam Computed Tomography scans will be performed immediately following tooth extractions (visit 2) and 6 months (visit 4) after extractions. Subjects will be examined over the course of 6 months. Investigators will be trained prior to participating in the study. Training will be undertaken during a site initiation visit and will include a detailed description of all study procedures including treatment methods, and measurement methods to obtain study endpoints. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04166890 -
Comparison of the Efficacy and Safety of Two Homologous Active Principles for Local Dental Anesthesia
|
Phase 4 | |
Completed |
NCT02155764 -
Ridge Preservation With New Class of Osteoplastic Materials
|
Phase 2 | |
Completed |
NCT01588444 -
Ridge Preservation After Tooth Extraction Using Cortical Versus Cancellous Freeze Dried Bone Allograft
|
N/A | |
Completed |
NCT00387140 -
A Study to Evaluate the Safety and Efficacy of an Investigational Drug in the Treatment of Postoperative Dental Pain (MK-2295-005)
|
Phase 2 | |
Recruiting |
NCT06245161 -
Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients
|
N/A | |
Recruiting |
NCT05615272 -
Treatment of Alveolar Osteitis: Traditional or Regenerative?
|
N/A | |
Completed |
NCT05101954 -
Platelet Rich Fibrin and Concentrated Growth Factors on Osseointegration of Immediate Implants
|
N/A | |
Completed |
NCT03985033 -
The Clinical and Biological Effects of Leucocyte and Platelet-rich Fibrin (L-PRF) on Post-extraction Sockets Healing
|
N/A | |
Completed |
NCT04082598 -
Antibiotic Therapy in Erupted Tooth Extractions
|
Phase 4 | |
Completed |
NCT01924390 -
Histological Comparison of Ridge Preservation Using Mineralized FDBA Alone Versus a Combined Mineralized-Demineralized Freeze Dried Bone Allograft
|
N/A | |
Completed |
NCT04930497 -
Vestibular Socket Therapy With and Without Bone Grafting
|
N/A | |
Completed |
NCT03191448 -
Ridge Preservation Using FDBA and a Collagen Wound Dressing in Molar Sites
|
N/A | |
Completed |
NCT03211312 -
Prediction Model of Cardiac Risk for Dental Extraction in Elderly Patients With Cardiovascular Diseases
|
||
Withdrawn |
NCT06038695 -
Immediate Implant Placement Using Volume-Stable Collagen Matrix Combined With rhPDGF-BB
|
N/A | |
Completed |
NCT05845437 -
On Adequacy of Referrals to Oral and Maxillofacial Surgery
|
||
Recruiting |
NCT05220462 -
Remimazolam vs Midazolam Cognitive and Motor Recovery After Intravenous Conscious Sedation for Dental Extractions.
|
Phase 3 | |
Active, not recruiting |
NCT03943680 -
Plasma Rich in Growth Factors in Post-extraction Sockets
|
N/A | |
Recruiting |
NCT05106855 -
Comparative Study of Immediate Single Unit Implants in Early Loading Protocols, With or Without Photobiomodulation.
|
N/A | |
Completed |
NCT03487718 -
A 14 Weeks Longitudinal Study to Investigate the Effect of Leukocyte- Platelet Rich Fibrin Plug on the Quality of the Newly Formed Bone in Ridge Preservation Procedure Following a Tooth Extraction. It is a Clinical, Radiographic and Histomorphometric Study.
|
N/A | |
Active, not recruiting |
NCT04705181 -
The Indications of First Molar Extraction at Tufts University, School of Dental Medicine
|