Tooth Decay Clinical Trial
Official title:
Preventive Treatment Approach of Early Caries Lesions With Contemporary Methods of Remineralization
The purpose of this study is to evaluate
1. the additional therapeutic benefit of Curodont Repair for the treatment early occlusal
carious lesions on permanent teeth in children compared fluoride varnish alone
2. the tooth gel Curodont Protect when using it after Curodont Repair instead of fluoride
varnish
Objectives: The purpose of this study is to evaluate
1. the additional therapeutic benefit of Curodont Repair for the treatment early occlusal
carious lesions on permanent teeth in children compared fluoride varnish alone
2. the tooth gel Curodont Protect when using it after Curodont Repair instead of fluoride
varnish
Methods: 90 patients with early occlusal lesions (ICDAS-II:2-3) on permanent molars and
pre-molars will be allocated in this randomized, controlled, single blinded study to one of
the two test groups (Test1: Curodont™ Repair+Fluoride Varnish; Test2: Curodont
Repair+Curodont Protect) or control (Fluoride Varnish) group.
Lesions will be assessed at baseline and recalls after 3, 6 and 12 months regarding caries
activity (Nyvad), clinical status (ICDAS-II) and with Diagnodent®. Visual Analog Scale (VAS)
in addition to the Global Impression of Change Questionnaire will also be used for the
evaluation of the outcome.
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