Tongue Cancer Clinical Trial
Official title:
The Role of Direct Visual Fluorescence in Oral Examination
This clinical trial studies direct visual fluorescence in finding oral cancer in high-risk patients and patients undergoing routine dental care. Diagnostic procedures, such as direct visual fluorescence, may help find and diagnose oral cancer.
PRIMARY OBJECTIVES:
I. To assess the diagnostic benefit of the VELscope (direct visual fluorescence) inspection
in oral examination.
II. Efficacy of the VELscope in identifying dysplastic (premalignant) and malignant oral
mucosal lesions and in discriminating these lesions from common benign tissue changes.
III. Accuracy of clinical judgment versus VELscope findings. IV. Ability of the VELscope to
identify lesions or extent of lesions beyond what is clinically apparent.
OUTLINE:
Patients undergo conventional oral examination (COE) followed by direct visual fluorescence
examination (DVFE). Patients with tissue abnormalities found by COE or DVFE undergo scalpel
biopsy within 2 weeks.
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