Tobacco Cessation Clinical Trial
Official title:
mHealth Messaging to Motivate Quitline Use and Quitting Among Persons Living With HIV (PLWH) in Vietnam (M2Q2-HIV)
The intersection of smoking and HIV/AIDS poses a serious public health threat in Vietnam. Vietnam is dealing with these two challenges with parallel rather than integrated plans. Using a computer-tailored texting intervention, study investigators seek to promote the use of an underused, available, government-funded resource (the Quitline) and Nicotine Replacement Therapy (NRT) that the quitline provides, thus, promoting cessation among PLWH.
M2Q2-HIV [mHealth Messaging to Motivate Quitline Use and Quitting among Persons Living with HIV (PLWH) in Vietnam (M2Q2-HIV)] is an adaptation of a current computer-tailored smoking cessation intervention in Vietnam. Study investigators seek to promote underused government resources for public health (the Quitline) and Nicotine Replacement Therapy (NRT) among PLWH in a sustainable manner. Investigators will test M2Q2-HIV by conducting a randomized control trial with 600 PLWH smokers in two provinces in Northern Vietnam (26 clinics; 9,877 HIV patients). In Aim 1, study investigators will conduct formative work to prepare the M2Q2-HIV system for PLWH smokers. In Aim 2, the study team will randomize and follow smokers for six months. The study's effectiveness hypothesis will evaluate carbon monoxide (CO) verified, six-month, seven-day point prevalence cessation. Process hypotheses will evaluate self-efficacy, Quitline, and NRT use and test our hypothesized model that specific measured processes will partially mediate observed intervention effectiveness. Using qualitative interviews with key stakeholders and PLWH smokers, Aim 3 will support nationwide M2Q2-HIV dissemination assessing acceptability and contextual factors guided by the Practical, Robust Implementation and Sustainability Model (PRISM). This project builds upon a long-standing, successful collaboration between institutions in Vietnam (Ministry of Health, Bach Mai Quitline, Institute of Population Health and Development, Hanoi Medical University) and UMass Chan Medical School. The study team has expertise in smoking cessation, HIV intervention, including stigma related to concomitant substance use, and implementation of complex interventions. If proven effective, the Vietnam Ministry of Health is committed to incorporating M2Q2-HIV as a permanent part of the national infrastructure. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Enrolling by invitation |
NCT05415371 -
Persistent Poverty Counties Pregnant Women With Medicaid
|
N/A | |
| Not yet recruiting |
NCT04501016 -
A Stepped Care Approach to Treating Tobacco Use in Rural Veterans
|
Phase 2/Phase 3 | |
| Completed |
NCT01651611 -
Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents
|
N/A | |
| Completed |
NCT01570595 -
Positively Smoke Free on the Web (PSFW) for Smokers Living With HIV
|
Phase 1/Phase 2 | |
| Completed |
NCT01099384 -
Tobacco Cessation Treatment for Alaska Native Youth
|
Phase 1 | |
| Completed |
NCT01164306 -
The Impact of a Tobacco Control Intervention in African-American Families
|
N/A | |
| Recruiting |
NCT04865276 -
Adaptation and Evaluation of a Culturally and Gender Relevant Tobacco Cessation Among Women in Brazil: An Integrated mHealth Approach
|
N/A | |
| Recruiting |
NCT02103868 -
Medium Vs Low Intensity Intervention in Tobacco Cessation and Control in Zari Workers
|
N/A | |
| Completed |
NCT00836199 -
NicVAX/Placebo as an Aid for Smoking Cessation
|
Phase 3 | |
| Recruiting |
NCT05552534 -
Impact of an Intervention of Screening, Treatment Initiation and Referral to PROmote Smoking CEssation in Emergency Department Patients
|
N/A | |
| Completed |
NCT01482923 -
Tobacco Assessment and Intervention With Low-Income Persons Living With HIV-AIDS (PLWHA) in Community-Based AIDS Service Organizations
|
||
| Completed |
NCT05764343 -
The Effect of Immediate Smoking Cessation Interventions for Smokers With Chronic Airway Diseases
|
N/A | |
| Completed |
NCT01312480 -
Adolescent Smoking Cessation in Pediatric Primary Care
|
N/A | |
| Completed |
NCT03377738 -
Effectiveness of the Spirometry Test as a Motivational Tool for Quitting Tobacco in Primary Care
|
N/A | |
| Completed |
NCT03096145 -
Support Person Intervention to Promote a Smoking Helpline Among Under Resourced Smokers
|
N/A | |
| Completed |
NCT05095779 -
Incentives for Smoking Cessation in Persistent Poverty Counties
|
N/A | |
| Completed |
NCT03062709 -
A Study of Tobacco Smoke and Children With Respiratory Illnesses
|
N/A | |
| Completed |
NCT00750503 -
Workplace Tobacco Cessation And Oral Cancer Screening Study
|
Phase 3 | |
| Withdrawn |
NCT04340102 -
Development of a Scalable Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness
|
N/A | |
| Completed |
NCT01331226 -
Support Person Intervention to Promote a Smoking Helpline
|
N/A |