Sex Differences, Hormones & Smoking Cessation

Status Completed

Clinical Trial Summary

Data suggest that progesterone may improve smoking cessation outcomes perhaps by reducing impulsive behavior. However, the clinical literature on this topic is lacking. Therefore, in Project I we are proposing a double-blind randomized controlled trial to assess the role of exogenous progesterone on impulsivity and smoking cessation in a sample of males and females who are motivated to quit smoking.

Clinical Trial Description

Subjects will be stratified by sex and then randomly assigned to active progesterone (PRO) or placebo (PBO).

Telephone screening and visit invitation leads to the consent process and in-person screening including medical-psychiatric evaluation for inclusion/exclusion, then randomization and medication induction, stable medication with medication reduction and final evaluation for secondary outcomes. ;

Study Design

Related Conditions & MeSH terms

Tobacco Cessation

Clinical Trial Details

NCT number	NCT01744574
Study type	Interventional
Source	University of Minnesota - Clinical and Translational Science Institute
Contact
Status	Completed
Phase	N/A
Start date	December 2012
Completion date	July 27, 2017

View Details

See also
Status	Clinical Trial	Phase
Enrolling by invitation	`NCT05415371` - Persistent Poverty Counties Pregnant Women With Medicaid	N/A
Not yet recruiting	`NCT04501016` - A Stepped Care Approach to Treating Tobacco Use in Rural Veterans	Phase 2/Phase 3
Completed	`NCT01651611` - Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents	N/A
Completed	`NCT01570595` - Positively Smoke Free on the Web (PSFW) for Smokers Living With HIV	Phase 1/Phase 2
Completed	`NCT01099384` - Tobacco Cessation Treatment for Alaska Native Youth	Phase 1
Completed	`NCT01164306` - The Impact of a Tobacco Control Intervention in African-American Families	N/A
Recruiting	`NCT04865276` - Adaptation and Evaluation of a Culturally and Gender Relevant Tobacco Cessation Among Women in Brazil: An Integrated mHealth Approach	N/A
Recruiting	`NCT02103868` - Medium Vs Low Intensity Intervention in Tobacco Cessation and Control in Zari Workers	N/A
Completed	`NCT00836199` - NicVAX/Placebo as an Aid for Smoking Cessation	Phase 3
Recruiting	`NCT05552534` - Impact of an Intervention of Screening, Treatment Initiation and Referral to PROmote Smoking CEssation in Emergency Department Patients	N/A
Completed	`NCT01482923` - Tobacco Assessment and Intervention With Low-Income Persons Living With HIV-AIDS (PLWHA) in Community-Based AIDS Service Organizations
Completed	`NCT05764343` - The Effect of Immediate Smoking Cessation Interventions for Smokers With Chronic Airway Diseases	N/A
Completed	`NCT01312480` - Adolescent Smoking Cessation in Pediatric Primary Care	N/A
Completed	`NCT03377738` - Effectiveness of the Spirometry Test as a Motivational Tool for Quitting Tobacco in Primary Care	N/A
Completed	`NCT03096145` - Support Person Intervention to Promote a Smoking Helpline Among Under Resourced Smokers	N/A
Completed	`NCT05095779` - Incentives for Smoking Cessation in Persistent Poverty Counties	N/A
Completed	`NCT03062709` - A Study of Tobacco Smoke and Children With Respiratory Illnesses	N/A
Completed	`NCT00750503` - Workplace Tobacco Cessation And Oral Cancer Screening Study	Phase 3
Withdrawn	`NCT04340102` - Development of a Scalable Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness	N/A
Completed	`NCT01331226` - Support Person Intervention to Promote a Smoking Helpline	N/A