Tobacco Addiction Clinical Trial
Official title:
High Cessation Rates in Smokers Using Personal Vaporizers: A Prospective 6-month Pilot Study
E-cigarettes are proving to be an attractive long-term alternative to conventional
cigarettes. Although they may also help smokers to remain abstinent during their quit
attempt, recent clinical trials with first generation e-cigarettes have shown only modest
quit rates. Second generation devices may result in much higher quit rates. Their efficacy
and safety in long-term smoking cessation and/or smoking reduction studies have never been
investigated.
In this prospective proof-of-concept study we monitored modifications in smoking habits of
50 regular smokers (unwilling to quit) who were asked to switch to a second generation
device focusing on smoking reduction and smoking abstinence. Study participants were invited
to attend a total of five study visits: at baseline, week-4, week-8, week-12 and week-24.
Product usage, number of cigarettes smoked, and exhaled carbon monoxide (eCO) levels were
measured at each visit. Smoking reduction and abstinence rates were calculated. Adverse
events and participants' opinions of these products were also reviewed.
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT02544360 -
A Photoaging Mobile App Promoting Poster Campaign for Preventing Smoking in Secondary Schools
|
N/A | |
| Completed |
NCT00491335 -
HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers
|
N/A | |
| Completed |
NCT01785147 -
Efficacy and Safety of BP1.4979 in Smoking Cessation
|
Phase 2 | |
| Recruiting |
NCT01038414 -
Duration of Behavioral Counseling Treatment Needed to Optimize Smoking Abstinence
|
Phase 4 | |
| Completed |
NCT02000921 -
Reduced Nicotine Content Cigarettes and Tobacco Switching Behaviors
|
N/A |