Effects of Brachial Plexus Block on Tissue Oxygenation

Tissue Oxygenation Clinical Trial

— BrachialPlexus  

Official title:

Effects of Brachial Plexus Block Applied With Different Approaches on Tissue Oxygenation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05269251
• Other study ID #: 357
• Status: Completed
• Start date: April 12, 2021
• Est. completion date: August 1, 2022

Study information

• Verified date: February 2024
• Source: Gazi University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The aim of this study is to measure the effects of sympathetic blockade caused by peripheral nerve blocks performed with the axillary, infraclavicular and interscalene approach on tissue oxygenation with Near Infrared Spectroscopy (NIRS), to evaluate and compare the radial artery flow velocity and diameter in the blocked extremity, and to investigate whether there is a relationship with the quality of the sensory and motor block.

Description:

It has been reported that vasodilation after peripheral nerve blocks increases tissue oxygenation and increases arterial circulation on the ipsilateral side . Near Infrared Spectroscopy (NIRS), a noninvasive measurement method of tissue oxygen level, is used to measure regional hemoglobin oxygen saturation of arterial, venous and capillary blood .

Many studies have compared the effects of upper extremity peripheral nerve blocks on the onset, quality, extent, and postoperative pain of sensory and motor block through axillary, infraclavicular, supraclavicular and interscalene approaches.

The aim of this study is to measure the effects of sympathetic blockade caused by peripheral nerve blocks performed with the axillary, infraclavicular and interscalene approach on tissue oxygenation with Near Infrared Spectroscopy (NIRS), to evaluate and compare the radial artery flow velocity and diameter in the blocked extremity, and to investigate whether there is a relationship with the quality of the sensory and motor block.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 99
• Est. completion date: August 1, 2022
• Est. primary completion date: May 31, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• ASA I-III patients

• Patients between the ages of 18 and 65

• Patients who applied axillary block

• Patients who applied infraclavicular block

• Patients who applied interscalene block

Exclusion Criteria:

• Peripheral nerve disease a history

• History of thrombosis in the extremity to be blocked

• History of embolism in the extremity to be blocked

• Presence of neuropathy

Related Conditions & MeSH terms

• Tissue Oxygenation

Intervention

Device:
• Near Infrared Spectroscopy (NIRS)
After the brachial plexus block, the regional oxygen saturation (rSO2) was monitored for 30 minutes with the Regional Oximetry System (O3™, Masimo, Irvine, CA) and the radial artery diameter with ultrasound in the same period.

Locations

Country	Name	City	State
Turkey	Demet Coskun	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Gazi University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	tissue oxygenation	Measured from both extremities by Near Infrared Spectroscopy for 30 min after brachial nerve block.	30 minutes
Secondary	Radial artery diameter	measured on the side of the block after brachial nerve block	30 minutes